Emtricitabine/Rilpivirine/Tenofovir Disoproxil Fumarate Single-Tablet Regimen: A Guide to Its Use in HIV-1 Infection

被引：0
|
作者：
Katherine A. Lyseng-Williamson
Lesley J. Scott
机构：
[1] Adis,
来源：
Clinical Drug Investigation | 2012年 / 32卷
关键词：
Efavirenz; Tenofovir Disoproxil Fumarate; Virological Failure; Emtricitabine; Etravirine;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The once-daily, single-tablet regimen of emtricitabine/rilpivirine/tenofovir disoproxil fumarate (Eviplera™ [EU]; Complera™ [US]) provides a convenient option for antiretroviral therapy in treatment-naive patients with HIV-1 infection. In well designed trials in this patient population, rilpivirine plus emtricitabine/tenofovir disoproxil fumarate was noninferior to efavirenz plus emtricitabine/tenofovir disoproxil fumarate in terms of reducing viral HIV-1 RNA level to <50 copies/mL and was generally better tolerated than efavirenz plus emtricitabine/tenofovir disoproxil fumarate.
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页码：715 / 722
页数：7
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