Emtricitabine/Rilpivirine/Tenofovir Disoproxil Fumarate Single-Tablet Regimen: A Guide to Its Use in HIV-1 Infection

被引：0

作者：

Katherine A. Lyseng-Williamson

Lesley J. Scott

机构：

[1] Adis,

来源：

Clinical Drug Investigation | 2012年 / 32卷

关键词：

Efavirenz; Tenofovir Disoproxil Fumarate; Virological Failure; Emtricitabine; Etravirine;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The once-daily, single-tablet regimen of emtricitabine/rilpivirine/tenofovir disoproxil fumarate (Eviplera™ [EU]; Complera™ [US]) provides a convenient option for antiretroviral therapy in treatment-naive patients with HIV-1 infection. In well designed trials in this patient population, rilpivirine plus emtricitabine/tenofovir disoproxil fumarate was noninferior to efavirenz plus emtricitabine/tenofovir disoproxil fumarate in terms of reducing viral HIV-1 RNA level to <50 copies/mL and was generally better tolerated than efavirenz plus emtricitabine/tenofovir disoproxil fumarate.

引用

页码：715 / 722

页数：7

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