Glycerol production by Candida krusei employing NaCl as an osmoregulator in batch and continuous fermentations

被引：1
|
作者：
Yongqiang Liu
Dehua Liu
Qiong Su
Dongming Xie
机构：
[1] Chinese Academy of Sciences,State Key Laboratory of Biochemical Engineering, Institute of Process Engineering
[2] Tsinghua University,Institute of Applied Chemistry, Department of Chemical Engineering
[3] Northwestern Minority University,Department of Chemistry
来源：
Biotechnology Letters | 2002年 / 24卷
关键词：
glycerol; multistage cascade bioreactor; NaCl; osmoregulator;
D O I：
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中图分类号：
学科分类号：
摘要：
Addition of 40 g NaCl l−1 to a chemically defined medium containing 140 g glucose l−1 in shake-flask culture improved glycerol production by Candida krusei from 16.5 g l−1 to 47.7 g l−1. With 40 g NaCl l−1 at a dilution rate of 0.065 h−1, glycerol concentration, glycerol yield (based on glucose consumed), and productivity in a four-stage cascade bioreactor were higher by 240%, 27% and 28%, respectively, than in a single-stage continuous culture system.
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页码：1137 / 1140
页数：3
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