Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies

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作者：
机构：
[1] Departments of Internal Medicine,Department of Human Genetics
[2] Epidemiology,Department of Twin Research and Genetic Epidemiology
[3] Erasmus Medical Center,Department of Hygiene and Epidemiology
[4] deCODE Genetics,Department of Biostatistics
[5] Reykjavik University,Department of Clinical Genetics
[6] Hebrew SeniorLife,Department of Endocrinology and Metabolism
[7] Harvard Medical School,The University of Western Australia and Department of Endocrinology & Diabetes
[8] Department of Medicine,undefined
[9] McGill University,undefined
[10] Kings College London,undefined
[11] University of Ioannina School of Medicine,undefined
[12] School of Public Health,undefined
[13] Boston University,undefined
[14] Wellcome Trust Sanger Institute,undefined
[15] McGill University and Genome Quebec Innovation Centre,undefined
[16] Erasmus MC,undefined
[17] Faculty of Medicine,undefined
[18] University of Iceland,undefined
[19] University Hospital,undefined
[20] School of Medicine & Pharmacology,undefined
[21] Sir Charles Gairdner Hospital,undefined
[22] Rheumatic Diseases Unit,undefined
[23] Institute of Genetics and Molecular Medicine,undefined
[24] Western General Hospital,undefined
[25] University of Edinburgh,undefined
[26] Center for Genetic Epidemiology and Modeling,undefined
[27] Tufts Medical Center,undefined
[28] Tufts University School of Medicine,undefined
[29] Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA).,undefined
来源：
Nature Genetics | 2009年 / 41卷
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摘要：
Fernando Rivadeneira and colleagues report findings from a large-scale meta-analysis of genome-wide association studies for bone mineral density. The loci identified in this study map to genes in signaling pathways relevant to bone metabolism and highlight the complex genetic architecture underlying osteoporosis.
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页码：1199 / 1206
页数：7
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