We present a case of a 39-year-old patient, who was diagnosed and treated for a tick-borne meningoencephalitis. Three months after the treatment he started to complain of annoying, cracks-resembling, rhythmical sounds, coming from the inside of his head to both his ears. Physical examination revealed rhythmical oscillations of the soft palate with a frequency of 100–120 per minute and a clock ticking noise synchronic with the palate tremor. Electromyography revealed continuous motor unit activity at rest in the tensor veli palatini muscle. Palatal myoclonus (PM) as a result of tick-borne meningoencephalitis was diagnosed. Treatment with several medications was started with no effect, then botulinum toxin was administered under EMG guidance to both sides of the patient’s soft palate with great improvement. A 5-year follow-up and continuation of botulinum toxin injections with only minor and reversible side effects proved the treatment efficacy and safety. In the article we present a case of symptomatic palatal myoclonus with ear click and shortly discuss its aetiology, types and treatment options. We also stress the efficacy and safety of PM treatment with repetitive injections of botulinum toxin.
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Karolinska Univ Hosp, Karolinska Inst, Infect Dis Unit, Inst Med, Solna, SwedenKarolinska Univ Hosp, Karolinska Inst, Infect Dis Unit, Inst Med, Solna, Sweden
Andersson, Charlotta Rydgard
Vene, Sirkka
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Swedish Inst Infect Dis Control, Solna, Sweden
Karolinska Inst, Stockholm, SwedenKarolinska Univ Hosp, Karolinska Inst, Infect Dis Unit, Inst Med, Solna, Sweden
Vene, Sirkka
Insulander, Mona
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Dept Communicable Dis Control & Prevent, Stockholm, SwedenKarolinska Univ Hosp, Karolinska Inst, Infect Dis Unit, Inst Med, Solna, Sweden
Insulander, Mona
Lindquist, Lars
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Karolinska Univ Hosp, Karolinska Inst, Infect Dis Unit, Inst Med, Huddinge, SwedenKarolinska Univ Hosp, Karolinska Inst, Infect Dis Unit, Inst Med, Solna, Sweden
Lindquist, Lars
Lundkvist, Ake
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Swedish Inst Infect Dis Control, Solna, Sweden
Karolinska Inst, Stockholm, SwedenKarolinska Univ Hosp, Karolinska Inst, Infect Dis Unit, Inst Med, Solna, Sweden
Lundkvist, Ake
Gunther, Goran
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Uppsala Univ, Akad Sjukhuset, Dept Med Sci, Uppsala, SwedenKarolinska Univ Hosp, Karolinska Inst, Infect Dis Unit, Inst Med, Solna, Sweden