Aims To evaluate the prevalence of, and identify risk factors associated with smokeless tobacco (SLT) use and cigarette smoking (CS) among Nigerian teenagers. Methods Using a validated self-administered questionnaire adapted from the Global Youth Tobacco Survey, we surveyed 1,272 teenagers selected from the five schools in Ilisan-Remo Nigeria regarding use of CS and SLT products. We used the Pearson chi-squared test and logistic regression to assess correlates of both SLT use and CS. Adjusted odds ratios (AOR) with 95 % confidence intervals (CI) were used to measure magnitudes of associations. Results Prevalence of ever users of SLT and CS were 5.0 % (CI: 3.8, 6.2) and 6.9 % (CI: 5.5, 8.3) respectively. Higher prevalence of SLT user was recorded among male (7.9 %), 18-19 years (11.1 %), those who had parents cigarette smokers (35.9 %), those whose best friends were cigarette smokers (47.1 %) and those working after school (9.4 %) compared with their counterparts (p<0.05). Similarly, higher prevalence of CSwas recorded among male (9.6 %), 18-19 years (12.7 %), those whose parents smoke (56.4 %), those whose best friends were cigarette smokers (100.0 %) and Muslims (11.1 %) compared with their counterparts. Major factors associated with SLT use were being a cigarette smokers (AOR029.9; CI: 16.5, 54.4), parents smoking (AOR016.1; CI: 9.0, 29.8) and having best friends who smoke (AOR015.1; CI: 7.0, 32.4). Main factors associated with CS included SLT use (AOR029.9; CI: 16.5, 54.4), parent smoking (AOR031.7; CI: 18.2, 55.4 and Muslim (AOR01.8; CI: 1.1, 2.9). Conclusion Prevention programmes aimed at reducing cigarette smoking need to be improved to reduce SLT use. The home and places of after school work must also be factored. © Springer-Verlag 2012.