Chiral ligand-exchange chromatography on an RP HPLC column coated with a new chiral selector derived froml-spinacine

被引：0
|
作者：
M. Remelli
D. Trombin
C. Conato
机构：
[1] University of Ferrara,Department of Chemistry
来源：
Chromatographia | 2002年 / 55卷
关键词：
Column liquid chromatography; Chiral separations; Ligand exchange; -; -decyl-; -spinacine; Amino acids;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A commercial reversed-phase (RP) C18 HPLC column has been dynamically coated with the chiral selectorNτ-n-decyl-l-spinacine and then loaded with copper(II) ions. Several racemic mixtures of underivatized amino acids and oligopeptides were resolved on the column by chiral ligand-exchange chromatography. The most important experimental conditions affecting column efficiency, retention, and selectivity (temperature and mobile phase flow rate and composition) were extensively investigated.
引用
收藏
页码：301 / 306
页数：5
相关论文
共 50 条
  • [31] Validated chiral separation of M9, a Mannich ketone compound, by chiral ligand-exchange chromatography
    Bi, Yujin
    Yang, Jing
    Lu, Xiumei
    Shao, Taili
    Dong, Jinhua
    Li, Famei
    JOURNAL OF SEPARATION SCIENCE, 2007, 30 (12) : 1839 - 1843
  • [32] Preparation of new hybrid organic/inorganic polymeric chiral stationary phases for ligand-exchange chromatography
    Song, Rui Juan
    Fu, Yu
    Yao, Na
    De Long, Yuan
    Huang, Tian Bao
    CHINESE CHEMICAL LETTERS, 2007, 18 (10) : 1250 - 1252
  • [33] Preparation of new hybrid organic/inorganic polymeric chiral stationary phases for ligand-exchange chromatography
    Rui Juan Song~(a
    Chinese Chemical Letters, 2007, (10) : 1250 - 1252
  • [34] Chiral ligand-exchange chromatography of amino acids using porous graphitic carbon coated with a dinaphthyl derivative of neamine
    Mustapha Zaher
    Corinne Ravelet
    Isabelle Baussanne
    Anne Ravel
    Catherine Grosset
    Jean-Luc Décout
    Eric Peyrin
    Analytical and Bioanalytical Chemistry, 2009, 393 : 655 - 660
  • [35] Chiral ligand-exchange chromatography of amino acids using porous graphitic carbon coated with a dinaphthyl derivative of neamine
    Zaher, Mustapha
    Ravelet, Corinne
    Baussanne, Isabelle
    Ravel, Anne
    Grosset, Catherine
    Decout, Jean-Luc
    Peyrin, Eric
    ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2009, 393 (02) : 655 - 660
  • [36] Descriptive structure-separation relationship studies in chiral ligand-exchange chromatography
    Natalini, Benedetto
    Macchiarulo, Antonio
    Sardella, Roccaldo
    Massarotti, Alberto
    Pellicciari, Roberto
    JOURNAL OF SEPARATION SCIENCE, 2008, 31 (13) : 2395 - 2403
  • [37] CHIRAL POLYMER AND OPTICAL RESOLUTION - LIGAND-EXCHANGE CHROMATOGRAPHY OF DL-HISTIDINE
    HE, BL
    JIN, RH
    KEXUE TONGBAO, 1988, 33 (22): : 1861 - 1865
  • [38] Separation of Fudosteine on an Achiral C18 Column by HPLC with Chiral Ligand-Exchange Selectors as Mobile Phase Additives
    Ma, J.
    Cao, J.
    Ding, M. J.
    Yuan, L. H.
    Zhai, M. J.
    Zhang, J.
    Zhang, Q.
    Li, F.
    Zhou, X. M.
    ACTA CHROMATOGRAPHICA, 2008, 20 (04) : 585 - 594
  • [39] NEW CHEMICALLY BONDED CHIRAL LIGAND-EXCHANGE CHROMATOGRAPHIC STATIONARY PHASES
    GUBITZ, G
    MIHELLYES, S
    KOBINGER, G
    WUTTE, A
    JOURNAL OF CHROMATOGRAPHY A, 1994, 666 (1-2) : 91 - 97
  • [40] NEW LIGAND-EXCHANGE MATERIALS FOR CHIRAL SEPARATIONS VIA TEMPLATE POLYMERIZATION
    RU, MT
    VIDYASANKAR, S
    ARNOLD, FH
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1995, 209 : 235 - CHED
12345