Norlabdane Compounds Containing Thiosemicarbazone or 1,3-Thiazole Fragments: Synthesis and Antimicrobial Activity

被引：0
|
作者：
S. P. Blaja
L. V. Lungu
K. I. Kuchkova
A. G. Ciocarlan
A. N. Barba
N. Vornicu
A. N. Aricu
机构：
[1] Institute of Chemistry,
[2] Metropolitan Center of Research T. A. B. O. R,undefined
来源：
Chemistry of Natural Compounds | 2021年 / 57卷
关键词：
norlabdane compounds; thiosemicarbazones; 1,3-thiazoles; synthesis; antimicrobial activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
New di-, tri-, tetra-, and pentanorlabdane compounds with thiosemicarbazone and 1,3-thiazole fragments were synthesized. Their antifungal and antibacterial activities were studied. The main advantages of this research were the available starting material, i.e., the natural labdane diterpenoid (–)-sclareol, which was isolated from renewable resources, and the high probability of biological activity combined with the low toxicity of these compounds because of their natural origin.
引用
收藏
页码：101 / 110
页数：9
相关论文
共 50 条
  • [31] Synthesis, Antimicrobial Evaluation and In silico Studies of Novel 2,4-disubstituted-1,3-thiazole Derivatives
    Masood, Mir Mohammad
    Irfan, Mohammad
    Alam, Shadab
    Hasan, Phool
    Queen, Aarfa
    Shahid, Shifa
    Zahid, Muhammad
    Azam, Amir
    Abid, Mohammad
    LETTERS IN DRUG DESIGN & DISCOVERY, 2019, 16 (02) : 160 - 173
  • [32] SYNTHESIS AND CHARACTERIZATION OF COPPER COMPLEXES: INTERACTION OF METALLIC CARBOXYLATES WITH 1,3-THIAZOLE LIGAND
    Seguel, Gloria V.
    Rivas, Bernabe L.
    Guillermo Contreras, J.
    JOURNAL OF THE CHILEAN CHEMICAL SOCIETY, 2013, 58 (04): : 1967 - 1970
  • [33] Reactivity of N-substituted alkenylidene hydrazinecarbothioamides toward tetracyanoethylene, an efficient synthesis stereoselective 1,3-thiazole compounds
    Hassan, Alaa A.
    Aly, Ashraf A.
    Mohamed, Nasr K.
    El-Shaieb, Kamal M.
    Makhlouf, Maysa M.
    Braese, Stefan
    Nieger, Martin
    Brown, Alan B.
    RESEARCH ON CHEMICAL INTERMEDIATES, 2020, 46 (02) : 1571 - 1585
  • [34] Synthesis and anti-Candida activity of novel 2-hydrazino-1,3-thiazole derivatives
    Maillard, Ludovic T.
    Bertout, Sebastien
    Quinonero, Ophelie
    Akalin, Gulsen
    Turan-Zitouni, Gulan
    Fulcrand, Pierre
    Demirci, Fatih
    Martinez, Jean
    Masurier, Nicolas
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 23 (06) : 1803 - 1807
  • [35] Synthesis of new 1,3-thiazole derivatives from 2(5)-hydroxyalkyl-1,3-thiazole-5(2)-carbaldehydes
    Sinenko, V. O.
    Slivchuk, S. R.
    Pil'o, S. G.
    Raenko, G. F.
    Brovarets, V. S.
    RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2016, 86 (07) : 1597 - 1603
  • [36] Synthesis of new 1,3-thiazole derivatives from 2(5)-hydroxyalkyl-1,3-thiazole-5(2)-carbaldehydes
    V. O. Sinenko
    S. R. Slivchuk
    S. G. Pil’o
    G. F. Raenko
    V. S. Brovarets
    Russian Journal of General Chemistry, 2016, 86 : 1597 - 1603
  • [37] Synthesis, Characterization and Drug-Likeness Predictions of 1,3-Thiazole and Benzothiazole Derivatives
    Naqvi, Arshi
    ORIENTAL JOURNAL OF CHEMISTRY, 2018, 34 (06) : 3134 - 3139
  • [38] Heterocyclic amino acids as scaffolds for the synthesis of functionalized chiral 1,3-thiazole and 1,3-selenazole derivatives
    Sackus, Algirdas
    Kveselyte, Aiste
    Malinauskiene, Vida
    Dzedulionyte, Karolina
    Bieliauskas, Aurimas
    Burinskas, Saulius
    Krikstolaityte, Sonata
    Slok, Frank
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 256
  • [39] Synthesis and BK channel-opening activity of 2-amino-1,3-thiazole derivatives
    Qi, Xiao-Lei
    Jo, Heeji
    Wang, Xue-Ying
    Ji, Tong-Tong
    Lin, Hai-Xia
    Park, Chul-Seung
    Cui, Yong-Mei
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 43
  • [40] Novel 1,3-Thiazole Analogues with Potent Activity against Breast Cancer: A Design, Synthesis, In Vitro, and In Silico Study
    Salem, Manar G.
    Abu El-Maaty, Dina M.
    El-Deen, Yassmina I. Mohey
    Elesawy, Basem H.
    El Askary, Ahmad
    Saleh, Asmaa
    Saied, Essa M.
    El Behery, Mohammed
    MOLECULES, 2022, 27 (15):
12345