Norlabdane Compounds Containing Thiosemicarbazone or 1,3-Thiazole Fragments: Synthesis and Antimicrobial Activity

被引:0
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作者
S. P. Blaja
L. V. Lungu
K. I. Kuchkova
A. G. Ciocarlan
A. N. Barba
N. Vornicu
A. N. Aricu
机构
[1] Institute of Chemistry,
[2] Metropolitan Center of Research T. A. B. O. R,undefined
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关键词
norlabdane compounds; thiosemicarbazones; 1,3-thiazoles; synthesis; antimicrobial activity;
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学科分类号
摘要
New di-, tri-, tetra-, and pentanorlabdane compounds with thiosemicarbazone and 1,3-thiazole fragments were synthesized. Their antifungal and antibacterial activities were studied. The main advantages of this research were the available starting material, i.e., the natural labdane diterpenoid (–)-sclareol, which was isolated from renewable resources, and the high probability of biological activity combined with the low toxicity of these compounds because of their natural origin.
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页码:101 / 110
页数:9
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