Neo-adjuvant chemotherapy followed by surgery versus surgery alone in high-risk patients with resectable colorectal liver metastases: the CHARISMA randomized multicenter clinical trial

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作者
Ninos Ayez
Eric P van der Stok
Hans de Wilt
Sandra A Radema
Richard van Hillegersberg
Rudi M Roumen
Gerard Vreugdenhil
Pieter J Tanis
Cornelis J Punt
Cornelis H Dejong
Rob L Jansen
Henk M Verheul
Koert P de Jong
Geke A Hospers
Joost M Klaase
Marie-Cecile Legdeur
Esther van Meerten
Ferry A Eskens
Nelly van der Meer
Bruno van der Holt
Cornelis Verhoef
Dirk J Grünhagen
机构
[1] Erasmus MC Cancer Institute,Department of Surgical Oncology
[2] Radboud University,Department of Surgical Oncology
[3] Nijmegen Medical Center,Department of Medical Oncology
[4] Radboud University,Department of Surgery
[5] Nijmegen Medical Center,Department of Surgery
[6] University Medical Center Utrecht,Department of Medical Oncology
[7] Máxima Medical Center,Department of Surgery
[8] Máxima Medical Center,Department of Medical Oncology
[9] Academic Medical Center,Department of Surgery
[10] Academic Medical Center,Department of Medical Oncology
[11] Maastricht University Medical Center,Department of Medical Oncology
[12] Maastricht University Medical Center,Division of Hepato
[13] VU University Medical Center,Pancreato
[14] University Medical Center Groningen,Biliary Surgery and Liver Transplantation, Department of Surgery
[15] University of Groningen,Department of Medical Oncology
[16] University Medical Center Groningen,Department of Surgery
[17] Medisch Spectrum Twente,Department of Internal Medicine
[18] Medisch Spectrum Twente,Department of Medical Oncology
[19] Erasmus MC Cancer Institute,undefined
[20] Clinical Trial Center,undefined
[21] Erasmus MC Cancer Institute,undefined
来源
BMC Cancer | / 15卷
关键词
Colorectal liver metastases; Neo-adjuvant chemotherapy; Surgical resection; Clinical risk score;
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