Update on combined kidney-pancreas transplantation

被引:0
|
作者
Aly, M. G. [1 ,2 ]
Morath, C. [1 ]
Mehrabi, A. [3 ]
Zeier, M. [1 ]
机构
[1] Nierenzentrum Heidelberg, Neuenheimer Feld 162, D-69120 Heidelberg, Germany
[2] Assiut Univ, Internal Med Dept, Nephrol Unit, Assiut, Egypt
[3] Chirurg Univ Klin Heidelberg, Sekt Viszerale Organtransplantat, Heidelberg, Germany
来源
NEPHROLOGE | 2020年 / 15卷 / 03期
关键词
Renal insufficiency; Diabetes mellitus; Diabetic nephropathy; Beta cell replacement therapy; Immunosuppression; ANTITHYMOCYTE GLOBULIN INDUCTION; MYCOPHENOLATE-MOFETIL; GRAFT THROMBOSIS; SINGLE-CENTER; OUTCOMES; TACROLIMUS; ALEMTUZUMAB; EXPERIENCE;
D O I
10.1007/s11560-020-00422-w
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Combined kidney-pancreas transplantation has been established as the best treatment modality for type-1 diabetic patients with end-stage renal disease. Successful transplantation leads to insulin- as well as dialysis independence. Since administration of calcineurin-inhibitors as a gold standard of immunosuppression in kidney-pancreas transplantation as well as the improvement of surgical procedures, kidney-pancreas transplantation witnessed a breakthrough regarding the reduction of mortality and organ losses.
引用
收藏
页码:168 / 176
页数:9
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