One of the main risk factors of premature death in non-communicable diseases is physical inactivity, being as significant as hypertension, diabetes mellitus, and even smoking. It has been observed that interventions for carrying out physical activity (PA) in a communal environment have been very effective in terms of participation and adherence. The aim of this study is to prove the changes that occur on a physical level in a group of 46 patients on a regulated promotion plan for PA for health. The study consisted of a total of 15 weeks, during which a series of measurements were taken on the patients prior and post carrying out the program. There were significant changes in the undertaking of body mass index (p = 0.006), systolic and diastolic arterial pressure (p = 0.03 and p = 0.01, respectively), changes in attitude [degree of PA (METs, p ≤= 0.001)], changes in perceived quality of life (EuroQoL-VAS, p ≤= 0.001), as well as in the total number of risk factors (RFT, p = 0.03). These data confirm that a regulated program of PA is effective improving cardiovascular risk factors; improving all parameters of functional fitness studied; increasing the degree of PA; and increasing the subjective perception of patients’ health. Furthermore, it is verified that carrying out these types of programs is awarded a high degree of satisfaction by the participants.