Secukinumab in Active Rheumatoid Arthritis after Anti-TNFα Therapy: A Randomized, Double-Blind Placebo-Controlled Phase 3 Study

被引：0
|
作者：
Hasan Tahir
Atul Deodhar
Mark Genovese
Tsutomu Takeuchi
Jacob Aelion
Filip Van den Bosch
Sibylle Haemmerle
Hanno B. Richards
机构：
[1] Barts Health NHS Trust,
[2] Oregon Health and Science University,undefined
[3] Stanford University,undefined
[4] Keio University School of Medicine,undefined
[5] West Tennessee Research Institute,undefined
[6] Ghent University Hospital,undefined
[7] Novartis Pharma AG,undefined
来源：
Rheumatology and Therapy | 2017年 / 4卷
关键词：
ACR; Autoimmune; Biologic; Clinical trial; HAQ-DI; IL-17A; Randomized; Rheumatoid arthritis; Secukinumab; vdH-mTSS;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：475 / 488
页数：13
相关论文
共 50 条
  • [21] EFFICACY AND SAFETY OF SIRUKUMAB, AN ANTI-IL-6 CYTOKINE MONOCLONAL ANTIBODY, IN PATIENTS WITH ACTIVE RHEUMATOID ARTHRITIS DESPITE ANTI-TNF THERAPY: RESULTS FROM A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED GLOBAL PHASE 3 STUDY (SIRROUND-T)
    Pile, K.
    Aletaha, D.
    Tanaka, Y.
    Agarwal, P.
    Kurrasch, R.
    Tak, P.
    Popik, S.
    INTERNAL MEDICINE JOURNAL, 2017, 47 : 27 - 27
  • [22] The Efficacy and Safety of Piclidenoson vs Methotrexate in Early Rheumatoid Arthritis: Phase 3 Randomized, Double-blind, Placebo-controlled Study
    Reitblat, Tatiana
    Gurman-Balbir, Alexandra
    Harpaz, Zivit
    Farbstein, Motti
    Silverman, Michael
    Kerns, William
    Fishman, Pnina
    ARTHRITIS & RHEUMATOLOGY, 2021, 73 : 3564 - 3566
  • [23] Vitamin D and immunomodulation in early rheumatoid arthritis: A randomized double-blind placebo-controlled study
    Buondonno, Ilaria
    Rovera, Guido
    Sassi, Francesca
    Rigoni, Micol Maria
    Lomater, Claudia
    Parisi, Simone
    Pellerito, Raffaele
    Isaia, Giovanni Carlo
    D'Amelio, Patrizia
    PLOS ONE, 2017, 12 (06):
  • [24] SAFETY AND EFFICACY OF SBI-087 IN SUBJECTS WITH ACTIVE RHEUMATOID ARTHRITIS IN A PHASE 2 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY
    Damjanov, N.
    Tlustochowicz, M.
    Aelion, J.
    Dimic, A.
    Greenwald, M.
    Diehl, A.
    Bhattacharya, I.
    Menon, S.
    Gourley, I.
    ANNALS OF THE RHEUMATIC DISEASES, 2013, 71 : 60 - 61
  • [25] Apremilast in Patients With Active Rheumatoid Arthritis: A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study
    Genovese, Mark C.
    Jarosova, Katerina
    Cieslak, Dorota
    Alper, Jeffrey
    Kivitz, Alan
    Hough, Douglas R.
    Maes, Peter
    Pineda, Lilia
    Chen, Mindy
    Zaidi, Farrukh
    ARTHRITIS & RHEUMATOLOGY, 2015, 67 (07) : 1703 - 1710
  • [26] Secukinumab Provides Sustained Improvements in the Signs and Symptoms of Active Psoriatic Arthritis in Anti-TNF-Naive Patients and Those Previously Exposed to Anti-TNF Therapy: 52-Week Results from a Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial with Subcutaneous Dosing
    Kavanaugh, Arthur
    McInnes, Iain B.
    Mease, Philip J.
    Hall, Stephan
    Chinoy, Hector
    Kivitz, Alan J.
    Patekar, Manmath
    Wang, Zailong
    Mpofu, Shephard
    ARTHRITIS & RHEUMATOLOGY, 2015, 67
  • [27] TREATMENT OF ACTIVE RHEUMATOID-ARTHRITIS WITH SLOW INTRAVENOUS INJECTIONS OF THYMOPENTIN - A DOUBLE-BLIND PLACEBO-CONTROLLED RANDOMIZED STUDY
    MALAISE, MG
    FRANCHIMONT, P
    BACHANDERSEN, R
    GERBER, H
    STOCKER, H
    HAUWAERT, C
    DANNESKIOLDSAMSOE, B
    GROSS, D
    GERSCHPACHER, H
    BOLLA, K
    LANCET, 1985, 1 (8433): : 832 - 836
  • [28] Immunotherapy of acute rheumatoid arthritis (Double-blind, placebo-controlled study using Anti-IFN-γ and Anti-TNF-α antibodies).
    Loukina, G
    Sigidin, Y
    Pushkova, O
    Skurkovich, B
    Skurkovich, S
    CLINICAL IMMUNOLOGY, 2002, 103 (03) : S106 - S106
  • [29] EFFECTS OF HORMONE REPLACEMENT THERAPY IN RHEUMATOID-ARTHRITIS - A DOUBLE-BLIND PLACEBO-CONTROLLED STUDY
    MACDONALD, AG
    MURPHY, EA
    CAPELL, HA
    BANKOWSKA, UZ
    RALSTON, SH
    ANNALS OF THE RHEUMATIC DISEASES, 1994, 53 (01) : 54 - 57
  • [30] Efficacy of ixekizumab in patients with psoriatic arthritis: Results of a phase 3 randomized, double-blind, active- and placebo-controlled study
    Mease, Philip
    van der Heijde, Desiree
    Ritchlin, Christopher
    Cuchacovich, Rachel
    Shuler, Catherine
    Lin, Chen-Yen
    Vangerow, Harald
    Samanta, Suvajit
    Lee, Chin
    Gladman, Dafna
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2016, 74 (05) : AB248 - AB248
12345