Hepatocellular carcinoma: Intratumoral EpCAM-positive cancer stem cell heterogeneity identifies high-risk tumor subtype

被引:0
|
作者
Jenny Krause
Johann von Felden
Christian Casar
Thorben W. Fründt
Johanna Galaski
Constantin Schmidt
Caroline Jung
Harald Ittrich
Sören A. Weidemann
Till Krech
Asmus Heumann
Jun Li
Lutz Fischer
Guido Sauter
Ansgar W. Lohse
Henning Wege
Kornelius Schulze
机构
[1] University Medical Centre Hamburg-Eppendorf,Department of Medicine
[2] University Medical Centre Hamburg-Eppendorf,Bioinformatics Core
[3] University Medical Centre Hamburg-Eppendorf,Department of Diagnostic and Interventional Radiology and Nuclear Medicine
[4] University Medical Centre Hamburg-Eppendorf,Department of Pathology
[5] University Medical Centre Hamburg-Eppendorf,Department of General, Visceral and Thoracic Surgery
[6] University Medical Centre Hamburg-Eppendorf,Department of Visceral Transplant Surgery
[7] University Medical Centre Hamburg-Eppendorf,Mildred Scheel Cancer Career Centre HaTriCS4
来源
BMC Cancer | / 20卷
关键词
Hepatocellular carcinoma; Cancer stem cell features; EpCAM; Intratumoral heterogeneity;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [21] Stem-cell transplantation for high-risk breast cancer
    Elfenbein, GJ
    NEW ENGLAND JOURNAL OF MEDICINE, 2003, 349 (01): : 80 - 82
  • [22] Heterogeneity for Stem Cell-Related Markers According to Tumor Subtype and Histologic Stage in Breast Cancer
    Park, So Yeon
    Lee, Hee Eun
    Li, Hailun
    Shipitsin, Michail
    Gelman, Rebecca
    Polyak, Kornelia
    CLINICAL CANCER RESEARCH, 2010, 16 (03) : 876 - 887
  • [23] Targeting liver cancer stem cell through EpCAM therapy targeted with chemotherapy endorse enhanced progression in hepatocellular carcinoma
    Sekar, Vasanthakumar
    Veerabathiran, Ramakrishnan
    Pandian, Arjun
    Sivamani, Ganesan
    EGYPTIAN LIVER JOURNAL, 2023, 13 (01)
  • [24] Targeting liver cancer stem cell through EpCAM therapy targeted with chemotherapy endorse enhanced progression in hepatocellular carcinoma
    Vasanthakumar Sekar
    Ramakrishnan Veerabathiran
    Arjun Pandian
    Ganesan Sivamani
    Egyptian Liver Journal, 13
  • [25] Primary Cutaneous Carcinosarcoma of the Basal Cell Subtype Should Be Treated as a High-Risk Basal Cell Carcinoma
    Bourgeault, Emilie
    Alain, Jimmy
    Gagne, Eric
    JOURNAL OF CUTANEOUS MEDICINE AND SURGERY, 2015, 19 (04) : 407 - 411
  • [26] Non-alcoholic steatohepatitis promotes EpCAM positive cancer stem cells mediated tumorigenesis in immunocompetent mouse model of hepatocellular carcinoma
    Pandit, Harshul
    Li, Yan
    Cui, Guozhen
    Li, Suping
    Li, Salina
    Martin, Robert C.
    CANCER RESEARCH, 2017, 77
  • [27] Quantified postsurgical small cell size CFCs and EpCAM+ circulating tumor stem cells with cytogenetic abnormalities in hepatocellular carcinoma patients determine cancer relapse
    Wang, Liang
    Li, Yilin
    Xu, Jing
    Zhang, Aiqun
    Wang, Xuedong
    Tang, Rui
    Zhang, Xinjing
    Yin, Hongfang
    Liu, Manting
    Wang, Daisy Dandan
    Lin, Peter Ping
    Shen, Lin
    Dong, Jiahong
    CANCER LETTERS, 2018, 412 : 99 - 107
  • [28] Tumor cell contamination of peripheral blood stem cell transplants and bone marrow in high-risk breast cancer patients
    R Schulze
    M Schulze
    A Wischnik
    S Ehnle
    K Doukas
    W Behr
    W Ehret
    G Schlimok
    Bone Marrow Transplantation, 1997, 19 : 1223 - 1228
  • [29] Tumor mutational burden (TMB), intratumoral genetic heterogeneity (ITGH) and BCG responsiveness in high-risk non-muscle invasive bladder cancer (NMIBC).
    Bastos, Diogo Assed
    Lima, Mariana
    Mattedi, Romulo Loss
    Dzik, Carlos
    Ribeiro-Filho, Leopoldo
    Cordeiro, Mauricio
    Nahas, William Carlos
    Souza, Jussara Michaloski
    Amano, Mariane
    Bettoni, Fabiana
    Buzatto, Vanessa
    dos Santos, Filipe Ferreira
    Barreiro, Rodrigo
    Favoretto Galante, Pedro Alexandre
    Camargo, Anamaria Aranha
    JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (15)
  • [30] Tumor cell contamination of peripheral blood stem cell transplants and bone marrow in high-risk breast cancer patients
    Schulze, R
    Schulze, M
    Wischnik, A
    Ehnle, S
    Doukas, K
    Behr, W
    Ehret, W
    Schlimok, G
    BONE MARROW TRANSPLANTATION, 1997, 19 (12) : 1223 - 1228