Controversies Concerning the Use of Neoadjuvant Systemic Therapy for Primary Breast Cancer

被引：0
|
作者：
Manfred Kaufmann
Thomas Karn
Eugen Ruckhäberle
机构：
[1] Johann Wolfgang Goethe University,Department of Obstetrics and Gynecology and Breast Unit
来源：
World Journal of Surgery | 2012年 / 36卷
关键词：
Trastuzumab; Sentinel Lymph Node Biopsy; Axillary Lymph Node Dissection; Inflammatory Breast Cancer; Prophylactic Contralateral Mastectomy;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The major aim of neoadjuvant systemic therapy is to improve prognosis by individualizing treatment. The proven benefits of neoadjuvant systemic therapy include reducing tumor burden, higher breast-conserving surgery, and the possibility of in vivo monitoring of response to treatment. Other goals of neoadjuvant treatment are the detection of new prognostic and predictive biomarkers and the investigation of new drugs and imaging modalities. Although many prospective trials have answered important questions regarding neoadjuvant systemic therapy, several topics remain controversial.
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页码：1480 / 1485
页数：5
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