News on Peripheral T-cell lymphoma

被引：0
|
作者：
Alexander Pichler
机构：
[1] Anna Spiegel Center of Translational Research ASCTR,Department of Medicine I, Division of Hematology and Hemostaseology
[2] Medical University of Vienna,undefined
来源：
memo - Magazine of European Medical Oncology | 2023年 / 16卷
关键词：
T‑cell lymphoma; Treatment; WHO subtypes; Brentuximab vedotin;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Peripheral T‑cell lymphomas (PTCL) are a heterogeneous group of rare lymphoid malignancies. Brentuximab vedotin plus cyclophosphamide, doxorubicin, and prednisone (BV+CHP, anti-CD30) is indicated as first-line treatment in the subgroup anaplastic large cell lymphoma (ALCL). Romidepsin plus cyclophosphamide, doxorubicin, vincristine, and prednisone (Ro-CHOP) is inferior to CHOP in PTCL; however, the subtype angioimmunoblastic T‑cell lymphoma (AITL) might favor Ro-CHOP. An increase of survival after consolidation with autologous stem cell transplantation (ASCT) in first line was found in a retrospective analysis. New antibody (anti-CD47 or anti-KIR3DL2) and CAR T/NK treatments are emerging and entering clinical trials.
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页码：17 / 20
页数：3
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