4-hydroxy-2-quinolones. 197*. The search for novel diuretics amongst halo-substituted 6-hydroxy-2-methyl-4-oxo-1,2-dihydro-4H-pyrrolo-[3,2,1-ij]quinoline-5-carboxylic acid anilides

被引：0

作者：

I. V. Ukrainets

N. Yu. Golik

A. L. Shemchuk

O. I. Naboka

Yu. V. Voronina

A. V. Turov

机构：

[1] National University of Pharmacy,

[2] Taras Shevchenko National University,undefined

来源：

Chemistry of Heterocyclic Compounds | 2011年 / 47卷

关键词：

anilides; 4-hydroxy-2-oxoquinoline-3-carboxylic acids; methylindoline; amidation; diuretic activity;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

A targeted synthesis of a series of halo-substituted 6-hydroxy-2-methyl-4-oxo-1,2-dihydro-4H-pyrrolo-[3,2,1-ij]quinoline-5-carboxylic acid anilides have been carried out. Peculiarites of the 1H NMR spectra and the results of investigating the diuretic activity of these compounds are discussed.

引用

页码：826 / 832

页数：6

共 50 条

[21] SYNTHESIS OF 8,9-DIFLUORO-2-METHYL-6-OXO-1,2-DIHYDROPYRROLO[3,2,1-IJ]QUINOLINE-5-CARBOXYLIC ACID
PARIKH, VD
FRAY, AH
KLEINMAN, EF
JOURNAL OF HETEROCYCLIC CHEMISTRY, 1988, 25 (05) : 1567 - 1569
[22] Synthesis of methyl 4-methyl-2-oxo-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinoline-6-carboxylate
Yu. A. Zhuravleva
A. V. Zimichev
M. N. Zemtsova
Yu. N. Klimochkin
Russian Journal of Organic Chemistry, 2011, 47 : 617 - 618
[23] 4-Hydroxy-2-quinolones 142. 4-Methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid anilides as potential diuretics
I. V. Ukrainets
N. L. Bereznyakova
V. A. Parshikov
O. I. Naboka
Chemistry of Heterocyclic Compounds, 2008, 44 : 178 - 183
[24] 4-hydroxy-2-quinolones 142. 4-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid anilides as potential diuretics
Ukrainets, I. V.
Bereznyakova, N. L.
Parshikov, V. A.
Naboka, O. I.
CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2008, 44 (02) : 178 - 183
[25] Synthesis of methyl 4-methyl-2-oxo-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinoline-6-carboxylate
Zhuravleva, Yu. A.
Zimichev, A. V.
Zemtsova, M. N.
Klimochkin, Yu. N.
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2011, 47 (04) : 617 - 618
[26] 4-hydroxy-2-quinolones. 108. N-R-amides of 9-fluoro-1-hydroxy-5-methyl-3- oxo-6,7-dihydro-3H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid and their antitubercular activity
Ukrainets I.V.
Sidorenko L.V.
Gorokhova O.V.
Shishkin O.V.
Turov A.V.
Chemistry of Heterocyclic Compounds, 2006, 42 (9) : 1208 - 1222
[27] 4-Hydroxy-2-quinolones. 110. Bromination of 1-R-4-hydroxy-2-oxo-1,2- dihydroquinoline-3-carboxylic acid anilides
Ukrainets I.V.
Tkach A.A.
Sidorenko L.V.
Gorokhova O.V.
Chemistry of Heterocyclic Compounds, 2006, 42 (10) : 1301 - 1307
[28] 4-Hydroxy-2-quinolones 126. 1-Hydroxy-3-oxo-5,6-dihydro-3H-pyrrolo[3,2,1- ij]quinoline-2-carboxylic acid hydrazide and its derivatives
Ukrainets I.V.
Tkach A.A.
Mospanova E.V.
Svechnikova E.N.
Chemistry of Heterocyclic Compounds, 2007, 43 (08) : 1014 - 1019
[29] 4-hydroxy-2-quinolones. 153*. Synthesis of hetarylamides of 4-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid
I. V. Ukrainets
N. L. Bereznyakova
V. A. Parshikov
Chemistry of Heterocyclic Compounds, 2009, 45 : 345 - 350
[30] 4-Hydroxy-2-quinolones. 123. Amidation of 2-bromomethyl-5-oxo-1,2-dihydro-5H-oxazolo[3,2-a]quinoline-4-carboxylic acid
Ukrainets, I. V.
Bereznyakova, N. L.
Turov, A. V.
Shishkina, S. V.
KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 2007, (07): : 1034 - 1042

← 1 2 3 4 5 →