A decade of discovery in cancer genomics

被引:0
|
作者
Kenneth Offit
机构
[1] Clinical Genetics Service,Department of Medicine
[2] Program in Cancer Biology and Genetics,Department of Medicine and Public Health
[3] Sloan-Kettering Institute,undefined
[4] Memorial Sloan Kettering Cancer Center,undefined
[5] Weill Cornell Medical College,undefined
[6] Cornell University,undefined
来源
关键词
D O I
暂无
中图分类号
学科分类号
摘要
Over the past decade, genetic testing for rare inherited mutations, such as BRCA1 and BRCA2 mutations, has been successfully incorporated into clinical practice. Next-generation sequencing of cancer-susceptibility genes and entire tumour genomes has transformed cancer care and prevention. The discoveries of new cancer syndromes have raised exciting opportunities and potential liabilities for cancer-care providers seeking to incorporate genomic approaches into preventive oncology practice.
引用
收藏
页码:632 / 634
页数:2
相关论文
共 50 条
  • [41] Microbial genomics in its second decade
    Schuster, SC
    Gottschalk, G
    [J]. CURRENT OPINION IN MICROBIOLOGY, 2005, 8 (05) : 561 - 563
  • [42] Genomics as it enters its second decade
    不详
    [J]. GENOMICS, 1997, 45 (02) : 243 - 243
  • [43] Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells
    Yang, Wanjuan
    Soares, Jorge
    Greninger, Patricia
    Edelman, Elena J.
    Lightfoot, Howard
    Forbes, Simon
    Bindal, Nidhi
    Beare, Dave
    Smith, James A.
    Thompson, I. Richard
    Ramaswamy, Sridhar
    Futreal, P. Andrew
    Haber, Daniel A.
    Stratton, Michael R.
    Benes, Cyril
    McDermott, Ultan
    Garnett, Mathew J.
    [J]. NUCLEIC ACIDS RESEARCH, 2013, 41 (D1) : D955 - D961
  • [44] Discovery of new breast cancer relevant genes using the cancer genomics public database
    Samant, Ritika R.
    Samant, Rajeev S.
    [J]. CANCER RESEARCH, 2016, 76
  • [45] Genomics and Proteomics Approaches for Biomarker Discovery in Sporadic Colorectal Cancer with Metastasis
    Gonzalez-Gonzalez, Maria
    Garcia Garcia, Jacinto
    Alcazar Montero, Jose Antonio
    Gonzalez Fernandez, Luis Miguel
    Bengoechea, Oscar
    Blanco Munez, Oscar
    Orfao, Alberto
    Sayagues, J. M.
    Fuentes, Manuel
    [J]. CANCER GENOMICS & PROTEOMICS, 2013, 10 (01) : 19 - 25
  • [46] Genomics-based anti-cancer drug discovery - Preface
    Devi, GR
    [J]. CURRENT PHARMACEUTICAL BIOTECHNOLOGY, 2004, 5 (05)
  • [47] PRESM: personalized reference editor for somatic mutation discovery in cancer genomics
    Cao, Chen
    Mak, Lauren
    Jin, Guangxu
    Gordon, Paul
    Ye, Kai
    Long, Quan
    [J]. BIOINFORMATICS, 2019, 35 (09) : 1445 - 1452
  • [48] The role of emerging genomics and proteomics technologies in cancer drug target discovery
    Onyango, P
    [J]. CURRENT CANCER DRUG TARGETS, 2004, 4 (02) : 111 - 124
  • [49] Advance in translational genomics based biomarkers for cancer management: discovery and application
    Zhao, Guodong
    Ge, Qinyu
    Lan, Wenjun
    Zheng, Bo
    Liang, Yuting
    [J]. FRONTIERS IN GENETICS, 2023, 14
  • [50] Discovery in cancer genomics by next-generation sequencing and data analysis
    Mardis, Elaine
    [J]. CANCER RESEARCH, 2011, 71