Immunopathogenesis of viral infections in neurological autoimmune disease

被引:0
|
作者
Mohammad Amin Habibi
Fatemeh Nezhad Shamohammadi
Taraneh Rajaei
Haideh Namdari
Mohammad Reza Pashaei
Hamid Farajifard
Sajjad Ahmadpour
机构
[1] Multiple Sclerosis Research Center,Pediatric Cell and Gene Therapy Research Center, Gene, Cell and Tissue Research Institute
[2] Neuroscience Institut,Department of Immunology, School of Medicine
[3] Tehran University of Medical Sciences,Department of Microbiology and Immunology, Faculty of Veterinary Medicine
[4] Tehran University of Medical Sciences,Department of Internal Medicine, School of Medicine
[5] Shiraz University of Medical Sciences,Patient Safety Research Center
[6] University of Tehran,undefined
[7] Iranian Tissue Bank and Research Center,undefined
[8] Imam Khomeini Hospital,undefined
[9] Tehran University of Medical Science,undefined
[10] Patient Safety Research Center,undefined
[11] Clinical Research Institute,undefined
[12] Urmia University of Medical Science,undefined
[13] Clinical Research Institute,undefined
[14] Urmia University of Medical Sciences,undefined
来源
BMC Neurology | / 23卷
关键词
Multiple sclerosis; Autoimmunity; Viral infections; Autoimmune reaction;
D O I
暂无
中图分类号
学科分类号
摘要
Autoimmune diseases develop due to self-tolerance failure in recognizing self and non-self-antigens. Several factors play a role in inducing autoimmunity, including genetic and environmental elements. Several studies demonstrated the causative role of viruses; however, some studies showed the preventive effect of viruses in the development of autoimmunity. Neurological autoimmune diseases are classified based on the targets of autoantibodies, which target intracellular or extracellular antigens rather than neurons. Several theories have been hypothesized to explain the role of viruses in the pathogenesis of neuroinflammation and autoimmune diseases. This study reviewed the current data on the immunopathogenesis of viruses in autoimmunity of the nervous system.
引用
收藏
相关论文
共 50 条
  • [1] Immunopathogenesis of viral infections in neurological autoimmune disease
    Habibi, Mohammad Amin
    Nezhad Shamohammadi, Fatemeh
    Rajaei, Taraneh
    Namdari, Haideh
    Pashaei, Mohammad Reza
    Farajifard, Hamid
    Ahmadpour, Sajjad
    [J]. BMC NEUROLOGY, 2023, 23 (01)
  • [2] Viral infections & autoimmune disease
    Backstrom, E.
    Chambers, B.
    Kristensson, K.
    Ljunggren, H. -G.
    [J]. JOURNAL OF NEUROVIROLOGY, 2002, 8 (SUPPL 1) : 30 - 31
  • [3] Viral infections & autoimmune disease
    M. Brahic
    P. Kennedy
    [J]. Journal of NeuroVirology, 2002, 8 : 30 - 31
  • [4] Molecular mimicry in autoimmune neurological disease after viral infection
    Roep, BO
    [J]. CURRENT MEDICINAL CHEMISTRY, 2003, 10 (19) : 1939 - 1943
  • [5] THE IMMUNOPATHOGENESIS AND IMMUNOTHERAPY OF AUTOIMMUNE-DISEASE
    KINGSLEY, G
    WATTS, R
    [J]. JOURNAL OF THE ROYAL COLLEGE OF PHYSICIANS OF LONDON, 1993, 27 (01): : 59 - 64
  • [6] Emerging Viral Infections and Their Impact on the Global Burden of Neurological Disease
    Munoz, Laura S.
    Garcia, Maria A.
    Gordon-Lipkin, Eliza
    Parra, Beatriz
    Pardo, Carlos A.
    [J]. SEMINARS IN NEUROLOGY, 2018, 38 (02) : 163 - 175
  • [7] Viral infections:: their elusive role in regulating susceptibility to autoimmune disease
    Flodström-Tullberg, M
    [J]. MICROBES AND INFECTION, 2003, 5 (10) : 911 - 921
  • [8] The role of regulatory T cells in immunopathogenesis and immunotherapy of viral infections
    Karkhah, Ahmad
    Javanian, Mostafa
    Ebrahimpour, Soheil
    [J]. INFECTION GENETICS AND EVOLUTION, 2018, 59 : 32 - 37
  • [9] Molecular mimicry, bystander activation, or viral persistence: Infections and autoimmune disease
    Fujinami, RS
    von Herrath, MG
    Christen, U
    Whitton, JL
    [J]. CLINICAL MICROBIOLOGY REVIEWS, 2006, 19 (01) : 80 - +
  • [10] Viral infections and their relationship to neurological disorders
    Wouk, Jessica
    Rechenchoski, Daniele Zendrini
    Rodrigues, Bianca Cerqueira Dias
    Ribelato, Elisa Vicente
    Faccin-Galhardi, Ligia Carla
    [J]. ARCHIVES OF VIROLOGY, 2021, 166 (03) : 733 - 753