The aim of this study is to characterize and dynamically monitor the progress of peripheral neuropathy induced by n-hexane by electromyography and nerve conduction velocity (NCV-EMG). Twenty-five patients with n-hexane poisoning from an electronic company were investigated in the year 2009. The occupational history of these workers was collected, and toxic substance exposure was identified. Neurologic inspection and regular NCV-EMG inspection were performed for all patients upon hospital admission and after 3, 6, and 12 months of treatment. NCV-EMG results shown that patients with n-hexane poisoning have simultaneous damage on motor and sensory nerves, of which sensory nerve damage was more severe. Motor nerves of the lower limbs were severe damaged than those of the upper limbs; whereas injury of sensory nerve in the upper limbs was more severe than that of the lower limbs. After treatment, clinical signs and symptoms of the patients were significantly improved. NCV-EMG result showed a delayed worsening at 3 months then gradually recovered after 12 months. Recovery of the motor nerve was better compared with sensory nerve, with upper limbs faster than that of the lower limbs.
机构:
Lab of Clinical and Experimental Immunology, Humanitas Clinical and Research CenterDepartment of Internal Medicine, A.O. San Paolo, University of Milan
机构:
Univ Lyon, Lyon, France
E Herriot Hosp, Digest Physiol, Hosp Civils Lyon, Lyon, France
Humanitas Res Hosp, Div Gastroenterol, Digest Endoscopy Unit, Milan, ItalyHosp, Lyon, France
Roman, Sabine
Rivory, Jerome
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Hosp, Lyon, FranceHosp, Lyon, France
Rivory, Jerome
Mion, Francois
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机构:
Univ Lyon, Lyon, France
E Herriot Hosp, Digest Physiol, Hosp Civils Lyon, Lyon, France
Humanitas Res Hosp, Div Gastroenterol, Digest Endoscopy Unit, Milan, ItalyHosp, Lyon, France
Mion, Francois
Ponchon, Thierry
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Hosp, Lyon, FranceHosp, Lyon, France
Ponchon, Thierry
Garros, Aurelien
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Univ Lyon, Lyon, France
E Herriot Hosp, Digest Physiol, Hosp Civils Lyon, Lyon, France
Humanitas Res Hosp, Div Gastroenterol, Digest Endoscopy Unit, Milan, ItalyHosp, Lyon, France
机构:
Capital Med Univ, Beijing Friendship Hosp, Dept Radiol, Beijing 100050, Peoples R ChinaCapital Med Univ, Beijing Friendship Hosp, Dept Radiol, Beijing 100050, Peoples R China
Liu, Daliang
Jia, Huijuan
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Liaocheng Peoples Hosp, Dept Radiol, Liaocheng 252000, Shandong, Peoples R ChinaCapital Med Univ, Beijing Friendship Hosp, Dept Radiol, Beijing 100050, Peoples R China
Jia, Huijuan
Fu, Yucun
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Liaocheng Peoples Hosp, Dept Radiol, Liaocheng 252000, Shandong, Peoples R ChinaCapital Med Univ, Beijing Friendship Hosp, Dept Radiol, Beijing 100050, Peoples R China
Fu, Yucun
He, Wen
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Capital Med Univ, Beijing Friendship Hosp, Dept Radiol, Beijing 100050, Peoples R ChinaCapital Med Univ, Beijing Friendship Hosp, Dept Radiol, Beijing 100050, Peoples R China
He, Wen
Ma, Daqing
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Capital Med Univ, Beijing Friendship Hosp, Dept Radiol, Beijing 100050, Peoples R ChinaCapital Med Univ, Beijing Friendship Hosp, Dept Radiol, Beijing 100050, Peoples R China