Therapeutic Applications for Adipose-Derived Stem Cells in Wound Healing and Tissue Engineering

被引：13

作者：

McCarthy M.E. ^{[1
]}

Brown T.A. ^{[1
]}

Bukowska J. ^{[1
,2
]}

Bunnell B.A. ^{[1
,3
,4
]}

Frazier T. ^{[5
,8
]}

Wu X. ^{[8
]}

Gimble J.M. ^{[1
,5
,6
,7
,8
]}

机构：

[1] Center for Stem Cell Research and Regenerative Medicine, Tulane University, New Orleans, LA

[2] Polish Academy of Science, Olsztyn

[3] Department of Pharmacology, Tulane University, New Orleans, LA

[4] Tulane National Primate Research Center, Tulane University, New Orleans, LA

[5] Department of Structural and Cell Biology, Tulane University, New Orleans, LA

[6] Department of Medicine, Tulane University, New Orleans, LA

[7] Department of Surgery, Tulane University, New Orleans, LA

[8] LaCell LLC and Obatala Sciences Inc, New Orleans, LA

来源：

Current Stem Cell Reports | 2018年 / 4卷 / 2期

关键词：

Adipose-derived stem cells; Cytokine; Pressure ulcers; Scaffold; Skin wound healing; Stromal vascular fraction;

D O I：

10.1007/s40778-018-0125-9

中图分类号：

学科分类号：

摘要：

Purpose of Review: The use of adipose-derived stem cells (ASCs) has garnered recent interest for their accessibility and potential utility in wound healing applications. The purpose of this review is to provide an overview of developments within the last 5 years regarding therapeutic use of ASCs in wound healing applications. Recent Findings: Recent studies have demonstrated that ASCs do not exert the majority of their effects through differentiation, as previously believed. Rather, when they improve healing, it is via secreted factors that promote vascularization and control inflammation. New therapeutic approaches reflect this shift in belief. Summary: ASC-based therapies can improve outcomes in the treatment of a variety of wound types. Questions about how to best implement ASCs in the clinical setting remain, and their answers will profoundly influence the utility and availability of ASC-based therapies. © 2018, Springer International Publishing AG, part of Springer Nature.

引用

页码：127 / 137

页数：10

共 50 条

[1] Adipose-Derived Stem Cells for Wound Healing Applications
Cherubino, Mario
Rubin, J. Peter
Miljkovic, Natasa
Kelmendi-Doko, Arta
Marra, Kacey G.
ANNALS OF PLASTIC SURGERY, 2011, 66 (02) : 210 - 215
[2] Adipose-derived stem cells for wound healing
Hassanshahi, Alireza
Hassanshahi, Mohammadhossein
Khabbazi, Samira
Hosseini-Khah, Zahra
Peymanfar, Yaser
Ghalamkari, Saman
Su, Yu-Wen
Xian, Cory J.
JOURNAL OF CELLULAR PHYSIOLOGY, 2019, 234 (06) : 7903 - 7914
[3] Role of adipose-derived stem cells in wound healing
Ul Hassan, Waqar
Greiser, Udo
Wang, Wenxin
WOUND REPAIR AND REGENERATION, 2014, 22 (03) : 313 - 325
[4] Adipose-Derived Stem Cells for Tissue Engineering and Regenerative Medicine Applications
Dai, Ru
Wang, Zongjie
Samanipour, Roya
Koo, Kyo-in
Kim, Keekyoung
STEM CELLS INTERNATIONAL, 2016, 2016
[5] Adipose-derived mesenchymal stem cells and wound healing Potential clinical applications in wound repair
Almalki, Sami G.
SAUDI MEDICAL JOURNAL, 2022, 43 (10) : 1075 - 1086
[6] A review: therapeutic potential of adipose-derived stem cells in cutaneous wound healing and regeneration
Peng Li
Xiutian Guo
Stem Cell Research & Therapy, 9
[7] A review: therapeutic potential of adipose-derived stem cells in cutaneous wound healing and regeneration
Li, Peng
Guo, Xiutian
STEM CELL RESEARCH & THERAPY, 2018, 9
[8] Therapeutic potential of exosomes from adipose-derived stem cells in chronic wound healing
Long, Chengmin
Wang, Jingru
Gan, Wenjun
Qin, Xinchi
Yang, Ronghua
Chen, Xiaodong
FRONTIERS IN SURGERY, 2022, 9
[9] The use of adipose-derived stem cells as sheets for wound healing
McLaughlin, Meghan M.
Marra, Kacey G.
ORGANOGENESIS, 2013, 9 (02) : 79 - 81
[10] Adipose-Derived Stem Cells New Treatment for Wound Healing?
Toyserkani, Navid Mohamadpour
Christensen, Marlene Louise
Sheikh, Soren Paludan
Sorensen, Jens Ahm
ANNALS OF PLASTIC SURGERY, 2015, 75 (01) : 117 - 123

← 1 2 3 4 5 →