Evaluation of the cost effectiveness of sirolimus versus tacrolimus for immunosuppression following renal transplantation in the UK

被引：0

作者：

Phil McEwan

Simon Dixon

Keshwar Baboolal

Pete Conway

Craig J. Currie

机构：

[1] Cardiff University,School of Mathematics

[2] University of Sheffield,School of Health and Related Research

[3] University Hospital of Wales,Department of Renal Medicine

[4] Wyeth Laboratories-UK,Health Economics

[5] University of Wales College of Medicine,Department of Medicine

[6] Cardiff Research Consortium,undefined

来源：

PharmacoEconomics | 2006年 / 24卷

关键词：

Tacrolimus; Peritoneal Dialysis; Acute Rejection; Sirolimus; Graft Survival;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Introduction: Immunosuppressive therapy is required to prevent graft rejection. Calcineurin inhibitors such as tacrolimus are paradoxically toxic to the kidney, whereas sirolimus (rapamycin; Rapamune®) is not generally associated with the nephrotoxicity of CNIs. The purpose of this study was to evaluate the relative cost utility of sirolimus versus tacrolimus for the primary prevention of graft rejection in renal transplant recipients in the UK.

引用

页码：67 / 79

页数：12

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