Radioimmunotherapy for Indolent B-Cell Non-Hodgkin Lymphoma in Relapsed, Refractory and Transformed Disease

被引:0
|
作者
Otto J. Visser
Lars R. Perk
Josée M. Zijlstra
Guus A.M.S. van Dongen
Peter C. Huijgens
Arjan A. van de Loosdrecht
机构
[1] VU University Medical Center,Department of Hematology
[2] VU University Medical Center,Department of Otolaryngology/Head and Neck Surgery
来源
BioDrugs | 2006年 / 20卷
关键词
Autologous Stem Cell Transplantation; Bone Marrow Involvement; Bone Marrow Infiltration; Tositumomab; Ibritumomab Tiuxetan;
D O I
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学科分类号
摘要
Radioimmunotherapy (RIT) is a new treatment modality that combines the benefits of radiotherapy and immunotherapy. In RIT, a radionuclide is coupled to a monoclonal antibody, directed against an antigen expressed on tumor cells. Recently, RIT has been introduced targeting the CD20 surface antigen, which is expressed on nearly all B-cell non-Hodgkin lymphomas (NHL).
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页码:201 / 207
页数:6
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