The role of pre-existing cross-reactive antibodies in determining the efficacy of vaccination in humans: study protocol for a randomized controlled trial

被引:0
|
作者
Jenny G Low
Limin Wijaya
Greg KY Li
Eleanor YL Lim
Aland KL Shum
Yin-Bun Cheung
Eng-Eong Ooi
机构
[1] Singapore General Hospital,Department of Infectious Diseases
[2] Singapore General Hospital,Singhealth Investigational Medicine Unit
[3] Duke-NUS Graduate Medical School,Centre for Quantitative Medicine
[4] Duke-NUS Graduate Medical School,Program in Emerging Infectious Diseases
来源
Trials | / 16卷
关键词
Live vaccination; Cross-reactive neutralizing antibodies; Innate immune response; Adaptive immune response;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [31] Efficacy of electroacupuncture for symptoms of menopausal transition: study protocol for a randomized controlled trial
    Zhishun Liu
    Yang Wang
    Huanfang Xu
    Jiani Wu
    Liyun He
    John Yi Jiang
    Shiyan Yan
    Ruosang Du
    Baoyan Liu
    Trials, 15
  • [32] Immune responses of lung transplant recipients against SARS-CoV-2 and common respiratory coronaviruses: Evidence for pre-existing cross-reactive immunity
    Bansal, Sandhya
    Fleming, Timothy
    Canez, Jesse
    Maine, Gabriel N.
    Bharat, Ankit
    Walia, Rajat
    Tokman, Sofya
    Smith, Michael A.
    Tiffany, Brian
    Bremner, Ross M.
    Mohanakumar, T.
    TRANSPLANT IMMUNOLOGY, 2023, 81
  • [33] Prevalence of Pre-Existing Antibodies Reactive To rHuPH20 in the Normal Adult Population: An Interim Analysis of an Ongoing Survey Study
    Rosengren, Sanna
    Souratha, Jennifer
    Conway, Dave
    Sugarman, Barry J.
    Muchmore, Douglas B.
    JOURNAL OF CLINICAL IMMUNOLOGY, 2014, 34 (03) : 379 - 379
  • [34] SARS-CoV-2 mRNA Vaccines Induce Cross-Reactive Antibodies to NL63 Coronavirus but Do Not Boost Pre-Existing Immunity Anti-NL63 Antibody Responses
    Tang, Weiyi
    Chang, Zi Wei
    Goh, Yun Shan
    Tan, Yong Jie
    Hor, Pei Xiang
    Loh, Chiew Yee
    Lye, David C.
    Young, Barnaby E.
    Ng, Lisa F. P.
    Tay, Matthew Zirui
    Renia, Laurent
    VACCINES, 2025, 13 (03)
  • [35] Effects of Lysulin™ supplementation on pre-diabetes: study protocol for a randomized controlled trial
    Priyanga Ranasinghe
    Ranil Jayawardena
    Lal Chandrasena
    Vivianne Noetzel
    John Burd
    Trials, 20
  • [36] Effects of Lysulin supplementation on pre-diabetes: study protocol for a randomized controlled trial
    Ranasinghe, Priyanga
    Jayawardena, Ranil
    Chandrasena, Lal
    Noetzel, Vivianne
    Burd, John
    TRIALS, 2019, 20 (1)
  • [37] A trial for the use of qigong in the treatment of pre and mild essential hypertension: a study protocol for a randomized controlled trial
    Ji-Eun Park
    Yan Liu
    Taeseob Park
    Sanghoon Hong
    Jung-Eun Kim
    Tae-Hun Kim
    Ae-Ran Kim
    So-Young Jung
    Hyoju Park
    Sun-Mi Choi
    Trials, 12
  • [38] A trial for the use of qigong in the treatment of pre and mild essential hypertension: a study protocol for a randomized controlled trial
    Park, Ji-Eun
    Liu, Yan
    Park, Taeseob
    Hong, Sanghoon
    Kim, Jung-Eun
    Kim, Tae-Hun
    Kim, Ae-Ran
    Jung, So-Young
    Park, Hyoju
    Choi, Sun-Mi
    TRIALS, 2011, 12
  • [39] Outcomes of usual chiropractic, harm & efficacy, the ouch study: study protocol for a randomized controlled trial
    Bruce F Walker
    Barrett Losco
    Brenton R Clarke
    Jeff Hebert
    Simon French
    Norman J Stomski
    Trials, 12
  • [40] Outcomes of Usual Chiropractic, Harm & efficacy, the OUCH study: study protocol for a randomized controlled trial
    Walker, Bruce F.
    Losco, Barrett
    Clarke, Brenton R.
    Hebert, Jeff
    French, Simon
    Stomski, Norman J.
    TRIALS, 2011, 12