Telomere length in a population of long-lived people of the northwestern region of Russia

被引:0
|
作者
Smirnova T.Y. [1 ]
Runov A.L. [1 ]
Vonsky M.S. [1 ]
Spivak D.L. [2 ]
Zakharchuk A.G. [3 ]
Mikhelson V.M. [1 ]
Spivak I.M. [1 ]
机构
[1] Institute of Cytology, Russian Academy of Sciences, St. Petersburg
[2] Bekhtereva Institute of the Human Brain, Russian Academy of Sciences, St. Petersburg
[3] Gerontological Medico-Social City Center, St. Petersburg
基金
俄罗斯基础研究基金会;
关键词
5HTR2A; HTTLPR; longevity; polymorphism of ACE genes; telomeres;
D O I
10.1134/S1990519X12050112
中图分类号
学科分类号
摘要
An interdisciplinary study was carried out of the telomere length and polymorphism of genes of the renin-angiotensin (ACE) and serotonin (5HTR2A and 5HTTLPR) systems in a population of old and very old inhabitants of northwestern Russia, as well as on their relationships to data from clinical and geriatric anamneses and psychological characteristics. By the method of factor analysis, a firm association was revealed between the telomere length and respondents' age in subgroups of old and long-living respondents. © 2012 Pleiades Publishing, Ltd.
引用
收藏
页码:465 / 471
页数:6
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