Repurposing MYC and E2F in the absence of RB

被引:0
|
作者
Joana Osorio
机构
[1] Temporary Acting Senior Editor,
[2] Nature Reviews,undefined
来源
关键词
D O I
暂无
中图分类号
学科分类号
摘要
This study shows the mechanism by which, in the absence of RB, MYC and E2F proteins drive unregulated cell proliferation in the intestine.
引用
收藏
页码:516 / 517
页数:1
相关论文
共 50 条
  • [41] Knockdown of c-Myc inhibits cell proliferation by negatively regulating the Cdk/Rb/E2F pathway in nasopharyngeal carcinoma cells
    Niu, Zhaoxia
    Liu, Huaying
    Zhou, Ming
    Wang, Heran
    Liu, Yukun
    Li, Xiayu
    Xiong, Wei
    Ma, Jian
    Li, Xiaoling
    Li, Guiyuan
    ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2015, 47 (03) : 183 - 191
  • [43] Selective Occupation by E2F and RB of Loci Expressed by RNA Polymerase III
    Sizer, Rebecca E.
    Butterfield, Sienna P.
    Hancocks, Lucy A.
    De Sousa, Leonor Gato
    White, Robert J.
    CANCERS, 2024, 16 (03)
  • [44] The Role and Clinical Implications of the Retinoblastoma (RB)-E2F Pathway in Gastric Cancer
    Wu, Tianyi
    Wu, Lizhao
    FRONTIERS IN ONCOLOGY, 2021, 11
  • [45] Prohibitin, a potential tumor suppressor, interacts with RB and regulates E2F function
    Wang, S
    Nath, N
    Adlam, M
    Chellappan, S
    ONCOGENE, 1999, 18 (23) : 3501 - 3510
  • [46] Erratum: Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F
    Gustavo Leone
    James DeGregori
    Rosalie Sears
    Laszlo Jakoi
    Joseph R. Nevins
    Nature, 1997, 387 : 932 - 932
  • [47] E2F activity is essential for survival of Myc-overexpressing human cancer cells
    Santoni-Rugiu, E
    Duro, D
    Farkas, T
    Mathiasen, IS
    Jäättelä, M
    Bartek, J
    Lukas, J
    ONCOGENE, 2002, 21 (42) : 6498 - 6509
  • [48] E2F activity is essential for survival of Myc-overexpressing human cancer cells
    Eric Santoni-Rugiu
    Dominique Duro
    Thomas Farkas
    Ida S Mathiasen
    Marja Jäättelä
    Jiri Bartek
    Jiri Lukas
    Oncogene, 2002, 21 : 6498 - 6509
  • [49] The Rb/E2F pathway and Ras activation regulate RecQ helicase gene expression
    Liu, Yongqing
    El-Naggar, Shahenda
    Clem, Brian
    Chesney, Jason
    Dean, Douglas C.
    BIOCHEMICAL JOURNAL, 2008, 412 (299-306) : 299 - 306
  • [50] LXCXE-independent chromatin remodeling by Rb/E2f mediates neuronal quiescence
    Andrusiak, Matthew G.
    Vandenbosch, Renaud
    Dick, Fred A.
    Park, David S.
    Slack, Ruth S.
    CELL CYCLE, 2013, 12 (09) : 1416 - 1423