For affordable high-volume manufacture of sandwich panels with complex curvature and varying thickness, fabric skins and a core structure are simultaneously press-formed using a set of matched tools. A finite-element-based process simulation was developed, which takes into account shearing of the reinforcement skins, multi-axial deformation of the core structure, and friction at the interfaces. Meso-scale sandwich models, based on measured properties of the honeycomb cell walls, indicate that panels deform primarily in bending if out-of-plane movement of the core is unconstrained, while local through-thickness crushing of the core is more important in the presence of stronger constraints. As computational costs for meso-scale models are high, a complementary macro-scale model was developed for simulation of larger components. This is based on experimentally determined homogenised properties of the honeycomb core. The macro-scale model was employed to analyse forming of a generic component. Simulations predicted the poor localised conformity of the sandwich to the tool, as observed on a physical component. It was also predicted accurately that fibre shear angles in the skins are below the critical angle for onset of fabric wrinkling.