Photoredox-catalyzed [4+2] annulation of cyclobutylanilines with alkenes, alkynes, and diynes in continuous flow

被引：0

作者：

Jiang Wang

Theresa H. Nguyen

Nan Zheng

机构：

[1] University of Arkansas,Department of Chemistry and Biochemistry

来源：

Science China Chemistry | 2016年 / 59卷

关键词：

photocatalysis; continuous flow; N-cyclobutylaniline; [4+2]; annulation; visible light;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Continuous flow has recently emerged as a powerful enabling technology that greatly improves many reactions’ efficiency. Here, we apply the technology to intermolecular [4+2] annulation of cyclobutylanilines with alkenes, alkynes, and diynes by photoredox catalysis. An across-the-board improvement in the annulation’s efficiency is noticed. Moreover, a gram-scale annulation is successfully demonstrated in continuous flow using a much lower catalyst loading.

引用

页码：180 / 183

页数：3

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