How Important Are Gender Differences in Pharmacokinetics?

被引:0
|
作者
Bernd Meibohm
Ingrid Beierle
Hartmut Derendorf
机构
[1] College of Pharmacy,Department of Pharmaceutical Sciences
[2] University of Tennessee,Department of Clinical Pharmacy
[3] College of Pharmacy,Department of Pharmaceutics
[4] University of Tennessee,Department of Pharmaceutical Sciences
[5] College of Pharmacy,undefined
[6] University of Florida,undefined
[7] University of Tennessee,undefined
来源
Clinical Pharmacokinetics | 2002年 / 41卷
关键词
Clozapine; Oral Clearance; Fleroxacin; Diflunisal; Mizolastine;
D O I
暂无
中图分类号
学科分类号
摘要
Gender-related differences in pharmacokinetics have frequently been considered as potentially important determinants for the clinical effectiveness of drug therapy. The mechanistic processes underlying gender-specific pharmacokinetics can be divided into molecular and physiological factors.
引用
收藏
页码:329 / 342
页数:13
相关论文
共 50 条
  • [41] Gender-specific physiology: How real is it? How important is it?
    Legato, MJ
    INTERNATIONAL JOURNAL OF FERTILITY AND WOMENS MEDICINE, 1997, 42 (01) : 19 - 29
  • [42] How Important Is the Digital Divide? The Relation of Computer and Videogame Usage to Gender Differences in Mental Rotation Ability
    Melissa S. Terlecki
    Nora S. Newcombe
    Sex Roles, 2005, 53 : 433 - 441
  • [43] How important is the digital divide? The relation of computer and videogame usage to gender differences in mental rotation ability
    Terlecki, MS
    Newcombe, NS
    SEX ROLES, 2005, 53 (5-6) : 433 - 441
  • [44] Gender differences in pharmacokinetics and pharmacodynamics of methadone substitution therapy
    Graziani, Manuela
    Nistico, Robert
    FRONTIERS IN PHARMACOLOGY, 2015, 6
  • [45] Gender differences in depression and antidepressant pharmacokinetics and adverse events
    Frackiewicz, EJ
    Sramek, JJ
    Cutler, NR
    ANNALS OF PHARMACOTHERAPY, 2000, 34 (01) : 80 - 88
  • [46] Gender differences in the hepatic elimination and pharmacokinetics of lobeglitazone in rats
    Lee, Jong-Hwa
    Son, Jun-Hyeng
    Chae, Yoon-Jee
    Ahn, Sung Hoon
    Lee, Wooin
    Kim, Dae-Duk
    Chung, Suk-Jae
    BIOPHARMACEUTICS & DRUG DISPOSITION, 2015, 36 (06) : 410 - 415
  • [47] GENDER DIFFERENCES IN PHARMACOKINETICS AND PHARMACODYNAMICS OF PSYCHOTROPICS - FOCUS ON WOMEN
    DAWKINS, K
    POTTER, WZ
    PSYCHOPHARMACOLOGY BULLETIN, 1991, 27 (04) : 417 - 426
  • [48] Genetic, ethnic, and gender differences in the pharmacokinetics of antiretroviral agents
    Rotger M.
    Csajka C.
    Telenti A.
    Current HIV/AIDS Reports, 2006, 3 (3) : 118 - 125
  • [49] Gender-related differences in pharmacokinetics and their clinical significance
    Tanaka, E
    JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 1999, 24 (05) : 339 - 346
  • [50] Gender differences of alcohol pharmacokinetics in healthy Korean adults
    Nam, B.
    Ahn, M.
    Lee, B.
    Seo, J.
    Lee, S.
    Shim, S. -h.
    EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2016, 26 : S669 - S669