Mechanisms of Disease: mutations of G proteins and G-protein-coupled receptors in endocrine diseases

被引：0
|
作者：
Andrea G Lania
Giovanna Mantovani
Anna Spada
机构：
[1] Endocrine Unit,a Research Associate, G Mantovani is a Postdoctoral Fellow and A Spada is a Professor of Endocrinology at the Department of Medical Sciences
[2] University of Milan,undefined
[3] Fondazione IRCCS Ospedale Maggiore,undefined
[4] Policlinico,undefined
[5] Mangiagalli,undefined
来源：
Nature Clinical Practice Endocrinology & Metabolism | 2006年 / 2卷
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学科分类号：
摘要：
Many hormones use G-protein-coupled receptors and G proteins in the target cell to transduce their signals. A range of disease-causing mutations have been characterized that mimic states of hormone deficiency or excess. This Review describes these mutations, and their resultant clinical and biochemical features.
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页码：681 / 693
页数：12
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