The role of bacteria and pattern-recognition receptors in Crohn's disease

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作者
Si Ming Man
Nadeem O. Kaakoush
Hazel M. Mitchell
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[1] University of Cambridge,Department of Veterinary Medicine
[2] School of Biotechnology and Biomolecular Sciences,undefined
[3] The University of New South Wales,undefined
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摘要
Although bacteria are known to have an important role in Crohn's disease, no specific groups or a single bacterium have been definitively associated with the initiation of this disease. This Review presents advances in understanding the role of bacteria and the contribution of pattern-recognition receptors and autophagy in the pathogenesis of Crohn's disease.
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页码:152 / 168
页数:16
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