Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease

被引：0
|
作者：
Lars M. Ittner
Jürgen Götz
机构：
[1] Lars M. Ittner and Jürgen Götz are at the Alzheimer's and Parkinson's Disease Laboratory,
[2] Brain and Mind Research Institute,undefined
[3] The University of Sydney,undefined
[4] Camperdown,undefined
[5] 100 Mallett Street,undefined
[6] NSW 2050,undefined
[7] Australia.,undefined
来源：
Nature Reviews Neuroscience | 2011年 / 12卷
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中图分类号：
学科分类号：
摘要：
Amyloid-β and tau exert toxicity in Alzheimer's disease through mechanisms that are gradually becoming understood. This Progress article reviews recent findings regarding their possible interactions and synergistic effects at the synapse, and discusses how these effects may contribute to the pathogenesis of Alzheimer's disease.
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页码：67 / 72
页数：5
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