Structural polymorphism in F-actin

被引：0
|
作者：
Vitold E Galkin
Albina Orlova
Gunnar F Schröder
Edward H Egelman
机构：
[1] University of Virginia,Department of Biochemistry and Molecular Genetics
[2] Institute of Structural Biology and Biophysics,undefined
来源：
Nature Structural & Molecular Biology | 2010年 / 17卷
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D O I：
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学科分类号：
摘要：
Electron cryo-microscopy images of actin filaments (F-actin) allow the visualization of different conformational states, which can be classified into different groups. Further analyses reveal the plasticity of the subdomain 2 region and suggest that missense mutations related to disease affect F-actin structural dynamics.
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页码：1318 / 1323
页数：5
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