MicroRNA in lung cancer

被引：0

作者：

P-Y Lin

S-L Yu

P-C Yang

机构：

[1] Institute of Biomedical Sciences,Department of Internal Medicine

[2] Academia Sinica,Department of Clinical and Laboratory Sciences and Medical Biotechnology

[3] National Taiwan University Hospital,Division of Genomic Medicine

[4] National Taiwan University,undefined

[5] Research Center for Medical Excellence,undefined

[6] National Taiwan University,undefined

来源：

British Journal of Cancer | 2010年 / 103卷

关键词：

lung cancer; microRNA; oncogene; tumour suppressor; risk stratification; personalised medicine;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

MicroRNAs (miRNAs) are small non-protein-coding RNAs that function as endogenous negative gene regulators. Dysfunctions of miRNAs are frequently found in malignancies, including lung cancer. In this review, we summarise the current understanding of miRNAs in lung cancer tumourigenesis, and highlight their potential in overcoming drug resistance, abetting histological sub-classification techniques, and serving as biomarkers for lung cancer risk stratification and outcome prediction.

引用

页码：1144 / 1148

页数：4

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