Stereological and Biochemical Effects of Curcumin on the l-Methionine-Induced Cardiotoxicity in Rats

被引:0
|
作者
Atefeh Rahimi
Ali Rafati
Ali Noorafshan
Narges Karbalaei
Saied Karbalay-Doust
Maryam Naseh
机构
[1] Shiraz University of Medical Sciences,Histomorphometry and Stereology Research Center
[2] Shiraz University of Medical Sciences,Department of Physiology
[3] Shiraz University of Medical Sciences,Department of Anatomy
关键词
Homocysteine; Methionine; Curcumin; Cardiotoxicity; Stereology; Oxidative stress;
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学科分类号
摘要
Homocysteine (Hcys) is a risk factor involved in the development of cardiovascular diseases. Hcys-induced oxidative stress has been proposed as a major mechanism contributing to the cardiotoxicity. Curcumin (CUR), a powerful antioxidant, exhibits cardioprotective activity against cardiotoxicity. The present study aimed to study the ameliorative action of CUR against cardiotoxicity induced by l-Methionine (MET), a precursor of homocysteine on stereological and biochemical parameters in rats.
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页码:841 / 847
页数:6
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