The role of the hippocampus in goal-directed action is currently unclear; studies investigating this issue have produced contradictory results. Here we reconcile these contradictions by demonstrating that, in rats, goal-directed action relies on the dorsal hippocampus, but only transiently, immediately after initial acquisition. Furthermore, we found that goal-directed action also depends transiently on physical context, suggesting a psychological basis for the hippocampal regulation of goal-directed action control.
机构:
Kyoto Univ, Grad Sch Educ, Sakyo Ku, Kyoto 6068501, Japan
RIKEN, ERATO, Japan Sci & Technol Agcy, Wako, Saitama 3510198, JapanKyoto Univ, Grad Sch Educ, Sakyo Ku, Kyoto 6068501, Japan
Myowa-Yamakoshi, Masako
Scola, Celine
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Aix Marseille Univ, Res Ctr Psychol Cognit Language & Emot, F-13621 Aix En Provence 1, FranceKyoto Univ, Grad Sch Educ, Sakyo Ku, Kyoto 6068501, Japan
Scola, Celine
Hirata, Satoshi
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机构:
Hayashibara Biochemical Labs Inc, Great Ape Res Inst, Okayama 7060316, Japan
Kyoto Univ, Primate Res Inst, Inuyama, Aichi 4848506, JapanKyoto Univ, Grad Sch Educ, Sakyo Ku, Kyoto 6068501, Japan
机构:
Emory Univ, Grad Program Neurosci, Atlanta, GA 30322 USA
Emory Univ, Sch Med, Emory Natl Primate Res Ctr, Dept Pediat & Psychiat & Behav Sci, Atlanta, GA 30307 USAEmory Univ, Grad Program Neurosci, Atlanta, GA 30322 USA
Heaton, Elizabeth C.
Seo, Esther H.
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Emory Univ, Sch Med, Emory Natl Primate Res Ctr, Dept Pediat & Psychiat & Behav Sci, Atlanta, GA 30307 USAEmory Univ, Grad Program Neurosci, Atlanta, GA 30322 USA
Seo, Esther H.
Butkovich, Laura M.
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Emory Univ, Sch Med, Emory Natl Primate Res Ctr, Dept Pediat & Psychiat & Behav Sci, Atlanta, GA 30307 USAEmory Univ, Grad Program Neurosci, Atlanta, GA 30322 USA
Butkovich, Laura M.
Yount, Sophie T.
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Emory Univ, Sch Med, Emory Natl Primate Res Ctr, Dept Pediat & Psychiat & Behav Sci, Atlanta, GA 30307 USA
Emory Univ, Grad Program Mol & Syst Pharmacol, Atlanta, GA USAEmory Univ, Grad Program Neurosci, Atlanta, GA 30322 USA
Yount, Sophie T.
Gourley, Shannon L.
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Emory Univ, Grad Program Neurosci, Atlanta, GA 30322 USA
Emory Univ, Sch Med, Emory Natl Primate Res Ctr, Dept Pediat & Psychiat & Behav Sci, Atlanta, GA 30307 USA
Emory Univ, Grad Program Mol & Syst Pharmacol, Atlanta, GA USA
Childrens Healthcare Atlanta, Atlanta, GA USAEmory Univ, Grad Program Neurosci, Atlanta, GA 30322 USA