Evidence of Ternary Inclusion Complexes Formation Using Factorial Design and Determination of Their Formation Constant

Evidence of the interaction among the [PbAc]+ and[PbEDTA]-2 with the β-cyclodextrin (β-CD)is shown, using a 24 factorial design. The factors used werethe [Pb(II)], [β-CD], [Ac-] and [EDTA] concentrationsat pH = 6.2. The statistical results indicate that the changes inchemical response for these species are associated to theinteraction among these factors. Spectrophotometric andelectrochemical studies were undertaken to assess the interactions.The equilibrium constants for inclusion complexes were determinedFor β-CD-[PbAc]+ and β-CD-[PbEDTA]-2.