Expression and purification of a novel ZNF191 zinc finger proteinZNF191 protein and its truncated zinc finger region ZNF191 (243–368)

被引:0
|
作者
Yuqi Liu
Long Yu
Wenhao Yu
Shaolin Shi
Bingyun Sun
Guojun Wu
Zhongxian Huang
机构
[1] Fudan University,Department of Chemistry
[2] Fudan University,Institute of Genetics
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关键词
zinc finger protein; expression; purification; PTSA-18; inclusion body;
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摘要
ZNF191 is a new zinc finger gene which has a 1107 bp open reading frame (ORF) and encodes a 368 amino acid protein including a putative DNA-binding domain of four Cys2His2 zinc finger motifs at its C-terminal region. The ZNF191 clDNA is located in the chromosome 18q12.1 region where it is known that a variety of hereditary diseases are related to. Probably, this protein has potential function of stimulating the gene transcription.
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页码:245 / 252
页数:7
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