Frequencies of the DRB1, DQA1, DQB1 and TNFA alleles in immigrant population of west Siberia

被引：0
|
作者：
O. V. Golovanova
V. I. Konenkov
A. V. Shevchenko
M. V. Smolnikova
机构：
[1] Russian Academy of Medical Sciences,Research Institute of Clinical and Experimental Lymphology
[2] Russian Academy of Medical Sciences,Research Institute of Medical Problems of the North
来源：
Russian Journal of Genetics | 2009年 / 45卷
关键词：
Linkage Disequilibrium; DRB1 Allele; DRB1 Gene; TNFA Gene; DQB1 Gene;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Based on population analysis of the DRB1, DQA1, DQB1 and TNFA allele frequency distribution patterns, regional features of immunogenetic structure of the population of West Siberia were investigated. Statistically significant linkage disequilibrium within the HLA class II region, as well as between the TNFA and DRB1, DQA1, and DQB1 was demonstrated. Population frequency distribution patterns of two- and multilocus haplotypes were examined.
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页码：981 / 986
页数：5
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