Dynamics of protein evolution

被引:0
|
作者
Meeta Rani
机构
[1] University of Hyderabad,Department of Biochemistry, School of Life Sciences
[2] National University Hospital,Bioinformatics Centre, Lilly Lobby
来源
Journal of Biosciences | 1998年 / 23卷
关键词
Evolution; dynamical systems; chaos; fractals; proteins;
D O I
暂无
中图分类号
学科分类号
摘要
Protein sequences of the SWISS-PROT data bank were analysed by fractal techniques and harmonic analysis. In both cases, the results show the presence of self-affinity, a kind of self-similarity, in the sequences. Self-similarity is a sign of fractality and fractality is a consequence of a chaotic dynamical process. The evolution of the protein sequences is modelled as a dynamical system. The abundance of the fractal form in biology and creation of fractal forms as a result of “chaos” is already established. It may be noted that the word “chaos” here implies that most predictable processes can also become unpredictable under certain conditions, and that the most unpredictable processes are not as unpredictable as they are expected to be. In evolutionary dynamics, this allows scope for mutations and variations in otherwise predictable situations, potentially leading to increased diversity.
引用
收藏
页码:47 / 54
页数:7
相关论文
共 50 条
  • [31] The role of protein dynamics in the evolution of new enzyme function
    Campbell, Eleanor
    Kaltenbach, Miriam
    Correy, Galen J.
    Carr, Paul D.
    Porebski, Benjamin T.
    Livingstone, Emma K.
    Afriat-Jurnou, Livnat
    Buckle, Ashley M.
    Weik, Martin
    Hollfelder, Florian
    Tokuriki, Nobuhiko
    Jackson, Colin J.
    NATURE CHEMICAL BIOLOGY, 2016, 12 (11) : 944 - +
  • [32] Evolution of enzyme fold: Linking protein dynamics and catalysis
    Agarwal, Pratul K.
    BIOPHYSICAL JOURNAL, 2009, 96 (03) : 377A - 377A
  • [33] Evolution and designing enzymes for rapid protein dynamics and catalysis
    Schwartz, Steven
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253
  • [34] Modification of protein dynamics by directed evolution based on insertions and deletions
    Schenkmayerova, A.
    Pinto, G.
    Liskova, V.
    Emond, S.
    Hernychova, L.
    Bednar, D.
    Chaloupkova, R.
    Hollfelder, F.
    Damborsky, J.
    FEBS OPEN BIO, 2018, 8 : 400 - 400
  • [35] Lessons in Protein Design from Combined Evolution and Conformational Dynamics
    Tripathi, Swarnendu
    Waxham, M. Neal
    Cheung, Margaret S.
    Liu, Yin
    SCIENTIFIC REPORTS, 2015, 5
  • [36] Integrative avenues for exploring the dynamics and evolution of protein interaction networks
    Diss, Guillaume
    Filteau, Marie
    Freschi, Luca
    Leducq, Jean-Baptiste
    Rochette, Samuel
    Torres-Quiroz, Francisco
    Landry, Christian R.
    CURRENT OPINION IN BIOTECHNOLOGY, 2013, 24 (04) : 775 - 783
  • [37] Evol and ProDy for bridging protein sequence evolution and structural dynamics
    Bakan, Ahmet
    Dutta, Anindita
    Mao, Wenzhi
    Liu, Ying
    Chennubhotla, Chakra
    Lezon, Timothy R.
    Bahar, Ivet
    BIOINFORMATICS, 2014, 30 (18) : 2681 - 2683
  • [38] Antibody evolution constrains conformational heterogeneity by tailoring protein dynamics
    Zimmermann, Joerg
    Oakman, Erin L.
    Thorpe, Ian F.
    Shi, Xinghua
    Abbyad, Paul
    Brooks, Charles L., III
    Boxer, Steven G.
    Romesberg, Floyd E.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (37) : 13722 - 13727
  • [39] Picosecond Dynamics Evolution During Function For Photoactive Yellow Protein
    George, Deepu K.
    BIOPHYSICAL JOURNAL, 2009, 96 (03) : 585A - 585A
  • [40] A Probabilistic Model of Neutral and Selective Dynamics of Protein Network Evolution
    Dutkowski, Janusz
    Tiuryn, Jerzy
    JOURNAL OF COMPUTATIONAL BIOLOGY, 2013, 20 (09) : 631 - 642