A New 1,2-Seco-Flavan-3-ol from the Leaves of Cinnamomum camphora var. linaloolifera

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作者
Yao Zhang
Shilin Liu
Yuanan Chen
Zeyue Niu
Kaiwen Wu
Meiting Wu
Xiaoqin Zhang
Lin Ni
机构
[1] Fujian Agriculture and Forestry University,College of Plant Protection
[2] Fujian University of Traditional Chinese Medicine,College of Pharmacy
[3] Fujian Colleges and Universities Engineering Research Institute of Conservation & Utilization of Natural Bioresources,undefined
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chemical constituents; flavanols; HepG2;
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摘要
A new 1,2-seco-flavan-3-ol,(2S)-1-(3′′-methoxy-4′′-hydroxyphenyl)-3-(2′,6′-dimethoxy-4′-hydroxyphenyl)-propan-2-ol (1), together with nine known compounds (2–10) were isolated from the leaves of Cinnamomum camphora var. linaloolifera Y. Fujita. Their structures were identified by spectroscopic methods and comparison with reported references. Compounds 1, 2, and 7 have different degrees of inhibition on HepG2 cells, IC50 values vary between 50 and 110 μmol·L–1.
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页码:451 / 454
页数:3
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