4-alkyl-6-amino-4-N3,N5-diaryl-2-thioxo-1,2,3,4-tetrahydropyridine-3,5-dicarboxamides: I. Tandem synthesis and alkylation. Molecular and crystal structure of 6-allylsulfanyl-2-amino-4-isobutyl-N3,N5-di-m-tolyl-3,4-dihydropyridine-3,5-dicarboxamide

被引：0

作者：

V. D. Dyachenko

E. N. Karpov

机构：

[1] Shevchenko Lugansk National University,

来源：

Russian Journal of General Chemistry | 2013年 / 83卷

关键词：

Mass Spectrum; EtOH; General Chemistry; White Powder; Yellow Powder;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

4-Alkyl-6-amino-4-N3,N5-diaryl-2-thioxo-1,2,3,4-tetrahydropyridine-3,5-dicarboxamides were obtained via tandem synthesis involving the Knoevenagel reaction, Michael reaction and intramolecular condensation. Alkylation of the obtained dicarboxamides proceeds regioselectively at the S atom to form the corresponding thioethers. Structure of 6-allylsulfanyl-2-amino-4-isobutyl-N3,N5-di-m-tolyl-3,4-dihydropyridine-3,5-dicarboxamide was uniquely determined by XRD analysis.

引用

页码：1394 / 1401

页数：7

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