L-carnitine Modulates Cognitive Impairment Induced by Doxorubicin and Cyclophosphamide in Rats; Insights to Oxidative Stress, Inflammation, Synaptic Plasticity, Liver/brain, and Kidney/brain Axes

被引:0
|
作者
Olivia Fayez Morid
Esther T. Menze
Mariane G. Tadros
Mina Y. George
机构
[1] Ain Shams University,Department of Pharmacology and Toxicology, Faculty of Pharmacy
来源
关键词
Doxorubicin; Cyclophosphamide; Synaptic plasticity; Oxidative stress; Chemobrain; Inflammation;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:310 / 326
页数:16
相关论文
共 35 条
  • [21] Insulin Protects against Brain Oxidative Stress with an Apparent Effect on Episodic Memory in Doxorubicin-Induced Cognitive Dysfunction in Wistar Rats
    Ramalingayya, Grandhi Venkata
    Sonawane, Vishwajeet
    Cheruku, Sri Pragnya
    Kishore, Anoop
    Nayak, Pawan G.
    Kumar, Nitesh
    Shenoy, Rekha R.
    Nandakumar, Krishnadas
    JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY, 2017, 36 (02) : 121 - 130
  • [22] Agomelatine reduces brain, kidney and liver oxidative stress but increases plasma cytokine production in the rats with chronic mild stress-induced depression
    Arif Demirdaş
    Mustafa Nazıroğlu
    Gülin Özdamar Ünal
    Metabolic Brain Disease, 2016, 31 : 1445 - 1453
  • [23] Agomelatine reduces brain, kidney and liver oxidative stress but increases plasma cytokine production in the rats with chronic mild stress-induced depression
    Demirdas, Arif
    Naziroglu, Mustafa
    Unal, Gulin Ozdamar
    METABOLIC BRAIN DISEASE, 2016, 31 (06) : 1445 - 1453
  • [24] Nose-to-brain delivery of chrysin transfersomal and composite vesicles in doxorubicin-induced cognitive impairment in rats: Insights on formulation, oxidative stress and TLR4/NF-kB/NLRP3 pathways
    Ibrahim, Shaimaa S.
    Elseoud, Omar G. Abo
    Mohamedy, Mohamed H.
    Amer, Mohamed M.
    Mohamed, Youssef Y.
    Elmansy, Shehab A.
    Kadry, Mohamed M.
    Attia, Ahmed A.
    Fanous, Ragy A.
    Kamel, Mahmoud S.
    Solyman, Youssef A.
    Shehata, Mazen S.
    George, Mina Y.
    NEUROPHARMACOLOGY, 2021, 197
  • [25] Brain-targeted lycopene-loaded microemulsion modulates neuroinflammation, oxidative stress, apoptosis and synaptic plasticity in β-amyloid-induced Alzheimer's disease mice
    Guo, Yunliang
    Fan, Zhongyu
    Zhao, Shuo
    Yu, Wei
    Hou, Xunyao
    Nie, Shanjing
    Xu, Song
    Zhao, Cheng
    Han, Junting
    Liu, Xueping
    NEUROLOGICAL RESEARCH, 2023, 45 (08) : 753 - 764
  • [26] Chlorpyrifos-induced oxidative stress and tissue damage in the liver, kidney, brain and fetus in pregnant rats:: The protective role of the butanolic extract of Paronychia argentea L.
    Zama, D.
    Meraihi, Z.
    Tabibel, S.
    Benayssa, W.
    Benayache, F.
    Benayache, S.
    Vlietinck, A. J.
    INDIAN JOURNAL OF PHARMACOLOGY, 2007, 39 (03) : 145 - 150
  • [27] Indole 3 carbinol attenuated memory impairment, oxidative stress, inflammation, and apoptosis in bilateral common carotid artery occlusion induced brain damage in rats
    Srikanth, Yadava
    Julius, Tuwune
    Gayathri, Meda
    Tuyishime, Honnete Samuel
    Gelege, Mtemi Daudi
    Kumar, Suda Satish
    Reddy, Dontiboina Harikrishna
    Chakravarthi, Guntupalli
    Ramakrishna, Kakarla
    3 BIOTECH, 2025, 15 (02)
  • [28] Attenuation of Lead-Induced Oxidative Stress in Rat Brain, Liver, Kidney and Blood of Male Wistar Rats by Moringa Oleifera Seed Powder
    Velaga, Manoj Kumar
    Daughtry, Lucius K.
    Jones, Angelica C.
    Yallapragada, Prabhakara Rao
    Rajanna, Sharada
    Rajanna, Bettaiya
    JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY, 2014, 33 (04) : 323 - 337
  • [29] Protective effects of Co-Q10, Ginkgo biloba, and l-carnitine on brain, kidney, liver, and endocrine system against sub-acute heavy metals toxicity in male rats
    Noor Ali Abdulidha
    Ausama Ayob Jaccob
    Muhsin S. G. AL-Moziel
    Toxicology and Environmental Health Sciences, 2020, 12 : 331 - 341
  • [30] Nose-to-brain delivery of chrysin transfersomal and composite vesicles in doxorubicin-induced cognitive impairment in rats: Insights on formulation, oxidative stress and TLR4/NF-kB/NLRP3 pathways (vol 197, 108738, 2021)
    Ibrahim, Shaimaa S.
    Elseoud, Omar G. Abo
    Mohamedy, Mohamed H.
    Amer, Mohamed M.
    Mohamed, Youssef Y.
    Elmansy, Shehab A.
    Kadry, Mohamed M.
    Attia, Ahmed A.
    Fanous, Ragy A.
    Kamel, Mahmoud S.
    Solyman, Youssef A.
    Shehata, Mazen S.
    George, Mina Y.
    NEUROPHARMACOLOGY, 2024, 254