Adenovirus-Mediated Thymidine Kinase Gene Therapy for Recurrent Ovarian Cancer: Expression of Coxsackie-Adenovirus Receptor and Integrins αvβ3 and αvβ5

被引：0
|
作者：
A. Hasenburg
D.-C. Fischer
X.-W. Tong
A. Rojas-Martinez
R. H. Kaufman
I. Ramzy
P. Kohlberger
M. Orlowska-Volk
E. Aguilar-Cordova
D. G. Kieback
机构：
[1] University Medical Center,Department of Obstetrics and Gynecology 1, Department of Pathology
[2] Baylor College of Medicine,Department of Obstetrics and Gynecology, Department of Pediatrics/Hematology
[3] Harvard Gene Therapy Initiative,Oncology, and Department of Pathology
[4] University Medical Center,Department of Obstetrics and Gynecology
来源：
The Journal of the Society for Gynecologic Investigation: JSGI | 2002年 / 9卷 / 3期
关键词：
Recurrent ovarian cancer; thymidine kinase gene therapy; intraperitoneal therapy; CAR; integrins αvβ3 and αvβ5;
D O I：
10.1177/107155760200900310
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：174 / 180
页数：6
相关论文
共 50 条
  • [21] Persistent Adenovirus-mediated Thymidine Kinase Gene Expression in Ovarian Cancer Cells Increases Cell Killing Efficacy Over Time
    Kieback, D. G.
    Delvoux, B.
    Romano, A.
    Ollig, S.
    Fischer, D. C.
    ANTICANCER RESEARCH, 2008, 28 (5A) : 2569 - 2575
  • [22] Improvement of gene therapy for ovarian cancer by using acyclovir instead of ganciclovir in adenovirus mediated thymidine kinase gene therapy
    Tong, XW
    Engehausen, DG
    Kaufman, RH
    Agoulnik, I
    Contant, C
    Freund, CTF
    Oehler, MK
    Kim, TE
    Hasenburg, A
    Woo, SLC
    Kieback, DG
    ANTICANCER RESEARCH, 1998, 18 (2A) : 713 - 718
  • [23] Increased expression of the coxsackie and adenovirus receptor downregulates αvβ3 and αvβ5 integrin expression and reduces cell adhesion and migration
    Majhen, Dragomira
    Stojanovic, Nikolina
    Speljko, Tea
    Brozovic, Anamaria
    De Zan, Tihana
    Osmak, Maja
    Ambriovic-Ristov, Andreja
    LIFE SCIENCES, 2011, 89 (7-8) : 241 - 249
  • [24] Adenovirus-mediated Thymidine Kinase Gene Therapy Induces Apoptosis in Human Epithelial Ovarian Cancer Cells and Damages PARP-1
    Kieback, D. G.
    IN VIVO, 2009, 23 (01): : 77 - 80
  • [25] Engineered expression of the Coxsackie B and adenovirus receptor (CAR) in human dendritic cells enhances recombinant adenovirus-mediated gene transfer
    Stockwin, LH
    Matzow, T
    Georgopoulos, NT
    Stanbridge, LJ
    Jones, SV
    Martin, IG
    Blair-Zajdel, ME
    Blair, GE
    JOURNAL OF IMMUNOLOGICAL METHODS, 2002, 259 (1-2) : 205 - 215
  • [26] Efficiency of adenovirus-mediated gene transfer to oropharyngeal epithelial cells correlates with cellular differentiation and human coxsackie and adenovirus receptor expression
    Hutchin, ME
    Pickles, RJ
    Yarbrough, WG
    HUMAN GENE THERAPY, 2000, 11 (17) : 2365 - 2375
  • [27] Adenoviral transduction efficiency and expression of the Coxsackie-adenovirus receptor (CAR) in 26 human ovarian cancer cell lines
    Runnebaum, IB
    Brüning, A
    Quist, S
    Albert, M
    Köhler, T
    Moebus, V
    CANCER GENE THERAPY, 1999, 6 (06) : S12 - S13
  • [28] Apical localization of the coxsackie-adenovirus receptor by glycosyl-phosphatidylinositol modification is sufficient for adenovirus-mediated gene transfer through the apical surface of human airway epithelia
    Walters, RW
    van't Hof, W
    Yi, SMP
    Schroth, MK
    Zabner, J
    Crystal, RG
    Welsh, MJ
    JOURNAL OF VIROLOGY, 2001, 75 (16) : 7703 - 7711
  • [29] Adenovirus-mediated thymidine kinase gene transduction in human epithelial ovarian cancer cell lines followed by exposure to ganciclovir
    Tong, XW
    Block, A
    Chen, SH
    Woo, SLC
    Kieback, DG
    ANTICANCER RESEARCH, 1996, 16 (4A) : 1611 - 1617
  • [30] Radiation therapy upregulates coxsackie-adenovirus receptor in prostate cancer cells and sensitizes prostate cancer to fas ligand gene therapy
    Mahdy, Ayman E.
    Liu, Xiang
    Cheng, Joe
    Elzawahry, Ahmed M.
    Turner, Lorianne S.
    Saad, Antonio F.
    Elojeimy, Saeed
    Hannun, Yusuf A.
    Keane, Thomas E.
    Taha, Mohammed
    Hammouda, Hisham M.
    Norris, James S.
    JOURNAL OF UROLOGY, 2007, 177 (04): : 179 - 180
12345