PegloticaseIn Treatment-Refractory Chronic Gout

被引：0
|
作者：
Katherine A. Lyseng-Williamson
机构：
[1] Adis,
[2] a Wolters Kluwer Business,undefined
来源：
Drugs | 2011年 / 71卷
关键词：
Uric Acid; Gout; Uric Acid Level; Infusion Reaction; Serum Uric Acid Level;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Intravenous pegloticase offers a novel approach to treating chronic gout refractory to conventional therapy. Pegloticase is a recombinant polyethylene glycol-conjugated form of uricase (a uric acid-specific enzyme lacking in humans) that catalyses the oxidation of uric acid to allantoin.
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页码：2179 / 2192
页数：13
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