Experimental Mycoplasma hominis Infection of the Genital Tract in BALB/c Mice

被引：0
|
作者：
M. M. Shkarupeta
V. N. Lazarev
V. M. Govorun
机构：
[1] Russian Ministry of Health,Institute of Physicochemical Medicine
来源：
Bulletin of Experimental Biology and Medicine | 2004年 / 137卷
关键词：
experimental infection;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We studied the ability of laboratory and clinical strains of Mycoplasma hominis to colonize the genital tract mucosa in BALB/c mice. Colonization with mycoplasma occurred only in mice receiving estrogen. Mycoplasma hominis strains obtained after 3-fold passage through the vaginal mucosa in mice and administered intravaginally in a dose of 0.5×108 CFU/ml caused infection in 100% animals. Inflammation in the lower genital tract was reduced by the 8th week after infection.
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页码：53 / 55
页数：2
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