Development of a multiparameter flow cytometric assay as a potential biomarker for homologous recombination deficiency in women with high-grade serous ovarian cancer

被引:0
|
作者
Jung-Min Lee
Nicolas Gordon
Jane B Trepel
Min-Jung Lee
Minshu Yu
Elise C Kohn
机构
[1] Women’s Malignancies Branch,
[2] Center for Cancer Research,undefined
[3] National Cancer Institute,undefined
[4] Developmental Therapeutics Branch,undefined
[5] Center for Cancer Research,undefined
[6] National Cancer Institute,undefined
关键词
Ovarian cancer; PARP inhibitor; Biomarkers; Flow cytometry; Peripheral blood mononuclear cells; γH2AX; MRE11; RAD51;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [1] Development of a multiparameter flow cytometric assay as a potential biomarker for homologous recombination deficiency in women with high-grade serous ovarian cancer
    Lee, Jung-Min
    Gordon, Nicolas
    Trepel, Jane B.
    Lee, Min-Jung
    Yu, Minshu
    Kohn, Elise C.
    [J]. JOURNAL OF TRANSLATIONAL MEDICINE, 2015, 13
  • [2] Characterisation of homologous recombination deficiency in paired primary and recurrent high-grade serous ovarian cancer
    Patel, Jai N.
    Braicu, Ioana
    Timms, Kirsten M.
    Solimeno, Cara
    Tshiaba, Placede
    Reid, Julia
    Lanchbury, Jerry S.
    Darb-Esfahani, Silvia
    Ganapathi, Mahrukh K.
    Sehouli, Jalid
    Ganapathi, Ram N.
    [J]. BRITISH JOURNAL OF CANCER, 2018, 119 (09) : 1060 - 1066
  • [3] Characterisation of homologous recombination deficiency in paired primary and recurrent high-grade serous ovarian cancer
    Jai N. Patel
    Ioana Braicu
    Kirsten M. Timms
    Cara Solimeno
    Placede Tshiaba
    Julia Reid
    Jerry S. Lanchbury
    Silvia Darb-Esfahani
    Mahrukh K. Ganapathi
    Jalid Sehouli
    Ram N. Ganapathi
    [J]. British Journal of Cancer, 2018, 119 : 1060 - 1066
  • [4] CLINICAL CHARACTERISTICS AND GENOMIC BIOMARKERS OF THE HOMOLOGOUS RECOMBINATION DEFICIENCY PHENOTYPE IN HIGH-GRADE SEROUS OVARIAN CANCER
    Vanderstichele, A.
    Nulens, K.
    Busschaert, P.
    Van Nieuwenhuysen, E.
    Han, S.
    Concin, N.
    Neven, P.
    Berns, E.
    Braicu, I.
    Castillo-Tong, A. Cacsire
    Mahner, S.
    Sehouli, J.
    Zeillinger, R.
    Smeets, D.
    Lambrechts, D.
    Vergote, I.
    [J]. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2017, 27 : 1818 - 1818
  • [5] Exploiting the Prevalence of Homologous Recombination Deficiencies in High-Grade Serous Ovarian Cancer
    Bouberhan, Sara
    Philp, Lauren
    Hill, Sarah
    Al-Alem, Linah F.
    Rueda, Bo
    [J]. CANCERS, 2020, 12 (05)
  • [6] Characteristics of homologous recombination deficiency (HRD) in paired primary and recurrent high-grade serous ovarian cancer (HGSOC).
    Patel, Jai Narendra
    Sehouli, Jahid
    Timms, Kirsten
    Solimeno, Cara
    Reid, Julia E.
    Lanchbury, Jerry S.
    Braicu, Ioana
    Darb-Esfahani, Silvia
    Ganapathi, Mahrukh
    Ganapathi, Ram N.
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (15)
  • [7] In-House Testing for Homologous Recombination Deficiency (HRD) in Mexican Patients with High-Grade Serous Ovarian Cancer
    Abreu-Gonzalez, Melania
    Santillan-Martinez, Rosalia
    Garcia-Ortiz, Ramiro
    Alvarez Ordorica, Oliver
    Martinez-Cannon, Bertha A.
    Hernandez Luis, Gisela
    Tellez Bernal, Eduardo
    Cortes Esteban, Patricia
    Blanco Vazquez, Yazmin C.
    Lopez Rosas, Gilberto
    Gomez Garcia, Eva M.
    Sanchez Llamas, Benito
    Rojas Toledo, Emma X.
    Martinez Gutierrez, Selena
    Azotla Vilchis, Coztli O.
    Rodriguez Munoz, Yolanda F.
    Munoz, Alexia
    Montes-Servin, Edgar
    Mendoza-Maldonado, Lucero
    Vaisman, Carolina E.
    Juarez Rodriguez, Rocio
    Flores Palacios, Jose A.
    Lara Torres, Cesar O.
    [J]. JOURNAL OF MOLECULAR DIAGNOSTICS, 2024, 26 (06): : S53 - S54
  • [8] Characteristics of homologous recombination deficiency (HRD) in paired primary and recurrent high-grade serous ovarian cancer (HGSOC)
    Patel, J.
    Sehouli, J.
    Timms, K.
    Solimeno, C.
    Reid, J.
    Lanchbury, J.
    Braicu, I.
    Darb-Esfahani, S.
    Ganapathi, M.
    Ganapathi, R.
    [J]. ANNALS OF ONCOLOGY, 2016, 27
  • [9] Homologous recombination deficiency status-based classification of high-grade serous ovarian carcinoma
    Hisamitsu Takaya
    Hidekatsu Nakai
    Shiro Takamatsu
    Masaki Mandai
    Noriomi Matsumura
    [J]. Scientific Reports, 10
  • [10] Homologous recombination deficiency status-based classification of high-grade serous ovarian carcinoma
    Takaya, Hisamitsu
    Nakai, Hidekatsu
    Takamatsu, Shiro
    Mandai, Masaki
    Matsumura, Noriomi
    [J]. SCIENTIFIC REPORTS, 2020, 10 (01)