HIF-1α increases the osteogenic capacity of ADSCs by coupling angiogenesis and osteogenesis via the HIF-1α/VEGF/AKT/mTOR signaling pathway

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作者
Shuang Song
Guanhua Zhang
Xutao Chen
Jian Zheng
Xiangdong Liu
Yiqing Wang
Zijun Chen
Yuxi Wang
Yingliang Song
Qin Zhou
机构
[1] Xi’an Jiaotong University,Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology
[2] The Fourth Military Medical University,Department of Oral Implants, School of Stomatology, State Key Laboratory of Military Stomatology and National Clinical Research Center for Oral Diseases and Shaanxi Engineering Research Center for Dental Materials and
[3] Peking University School and Hospital of Stomatology,Department of Prosthodontics
关键词
Hypoxia-inducible factor 1α; Adipose-derived stem cells; Osteointegration; Osteogenic differentiation; Stem cell transplantation; HIF-1α/VEGF/AKT/mTOR signaling pathway; Titanium implant;
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