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High prevalence of the CYP2B6 516G→T(*6) variant and effect on the population pharmacokinetics of efavirenz in HIV/AIDS outpatients in Zimbabwe
被引:0
|作者:
Christopher Nyakutira
Daniel Röshammar
Emmanuel Chigutsa
Prosper Chonzi
Michael Ashton
Charles Nhachi
Collen Masimirembwa
机构:
[1] African Institute of Biomedical Science and Technology (AiBST),Department of DMPK & BAC
[2] University of Zimbabwe,Department of Clinical Pharmacology, School of Health Sciences
[3] Sahlgrenska Academy at Göteborg University,Department of Pharmacology
[4] University of Zimbabwe,School of Pharmacy
[5] Harare City Council Health Services,undefined
来源:
关键词:
Efavirenz;
HIV/AIDS patients;
CYP2B6 polymorphism;
Pharmacokinetic modelling;
NONMEM;
D O I:
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页码:357 / 365
页数:8
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