Pharmacological effects of venlafaxine, a new antidepressant, given repeatedly, on the α1-adrenergic, dopamine and serotonin systems

被引：0
|
作者：
J. Maj
Z. Rogóż
机构：
[1] Institute of Pharmacology,
[2] Polish Academy of Sciences,undefined
[3] Kraków,undefined
[4] Poland,undefined
来源：
Journal of Neural Transmission | 1999年 / 106卷
关键词：
Keywords: Venlafaxine; repeated treatment; adaptive changes in neurotransmitter systems.;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Venlafaxine (VEN) is a representative of a new class of antidepressants (SNRIs) which inhibit selectively the uptake of serotonin and noradrenaline, but – in contrast to tricyclics – show no affinity for neurotransmitter receptors. The present study was aimed at determining whether repeated VEN (given twice daily for 14 days) induced adaptive changes in the α1-adrenergic, dopamine and serotonin systems, similar to those reported by us earlier for tricyclic antidepressants.
引用
收藏
页码：197 / 211
页数：14
相关论文
共 28 条
  • [21] Role of dopamine and serotonin systems in central sensory filtering processes: Effects of neonatal 6-OHDA lesions and 5-HT1A receptor active compounds on auditory gating in rat
    不详
    AMINO ACIDS, 2005, 29 (01) : 29 - 29
  • [22] Dopamine/serotonin receptor ligands VI.: Dibenz[g,j]-1-oxa-4-azacycloundecene and dibenz[d,g]-2-azacycloundecene:: Synthesis of two new heterocyclic ring systems as potential ligands for dopamine receptor subtypes
    Wittig, TW
    Enzensperger, C
    Lehmann, J
    HETEROCYCLES, 2003, 60 (04) : 887 - 898
  • [23] S 15535, a novel benzodioxopiperazine ligand of serotonin (5-HT)(1A) receptors .1. Interaction with cloned human (h)5-HT1A, dopamine hD(2)/hD(3) and h alpha(2A)-adrenergic receptors in relation to modulation of cortical monoamine release and activity in models of potential antidepressant activity
    Millan, MJ
    NewmanTancredi, A
    Rivet, JM
    Brocco, M
    Lacroix, P
    Audinot, V
    Cistarelli, L
    Gobert, A
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 1997, 282 (01): : 132 - 147
  • [24] Antidepressant and antipsychotic activity of new quinoline- and isoquinoline-sulfonamide analogs of aripiprazole targeting serotonin 5-HT1A/5-HT2A/5-HT7 and dopamine D2/D3 receptors
    Zajdel, Pawel
    Marciniec, Krzysztof
    Maslankiewicz, Andrzej
    Grychowska, Katarzyna
    Satala, Grzegorz
    Duszynska, Beata
    Lenda, Tomasz
    Siwek, Agata
    Nowak, Gabriel
    Partyka, Anna
    Wrobel, Dagmara
    Jastrzebska-Wiesek, Magdalena
    Bojarski, Andrzej J.
    Wesolowska, Anna
    Pawlowski, Maciej
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 60 : 42 - 50
  • [25] Discovery of a New Class of Potential Multifunctional Atypical Antipsychotic Agents Targeting Dopamine D3 and Serotonin 5-HT1A and 5-HT2A Receptors: Design, Synthesis, and Effects on Behavior
    Butini, Stefania
    Gemma, Sandra
    Campiani, Giuseppe
    Franceschini, Silvia
    Trotta, Francesco
    Borriello, Marianna
    Ceres, Nicoletta
    Ros, Sindu
    Coccone, Salvatore Sanna
    Bernetti, Matteo
    De Angelis, Meri
    Brindisi, Margherita
    Nacci, Vito
    Fiorini, Isabella
    Novellino, Ettore
    Cagnotto, Alfredo
    Mennini, Tiziana
    Sandager-Nielsen, Karin
    Andreasen, Jesper Tobias
    Scheel-Kruger, Jorgen
    Mikkelsen, Jens D.
    Fattorusso, Caterina
    JOURNAL OF MEDICINAL CHEMISTRY, 2009, 52 (01) : 151 - 169
  • [26] THE NEW ANTIDEPRESSANT TETRINDOLE-2,3,3A,4,5,6-HEXAHYDRO-8-CYCLOHEXYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE .1. PHARMACOLOGICAL STUDY OF EFFECTS ON THE CENTRAL-NERVOUS-SYSTEM
    ANDREYEVA, NI
    MASHKOVSKY, MD
    GOLOVINA, SM
    GORKIN, VZ
    KHIMIKO-FARMATSEVTICHESKII ZHURNAL, 1992, 26 (03): : 17 - 23
  • [27] NEURO-PHARMACOLOGICAL AND NEUROCHEMICAL EFFECTS OF 3-[4-(4-PHENYL-1,2,3,6-TETRAHYDROPYRIDYL-1)-BUTYL]INDOLE (EMD 23 448), A NEW, LONG-ACTING DOPAMINE AGONIST
    SEYFRIED, CA
    FUXE, K
    ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH, 1982, 32-2 (08): : 892 - 893
  • [28] PHARMACOLOGICAL STUDY OF PIROHEPTINE, A NEW ANTIPARKINSON DRUG, 3-(10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-5-YLIDENE)-1-ETHYL-2-METHYLPYRROLIDINE .1. EFFECTS ON DRUG-INDUCED TREMOR AND CATATONIA, AND ON ADRENERGIC ACTIONS
    HITOMI, M
    SATO, Y
    ITO, N
    KUMADAKI, N
    KUMADA, S
    FURUKAWA, T
    ARZNEIMITTEL-FORSCHUNG, 1972, 22 (06): : 953 - &
123